Alleviation of Severe Skin Insults Following High-Dose Irradiation with Isolated Human Fetal Placental Stromal Cells

November 2022 in “ International journal of molecular sciences ”

Boaz Adani, Eli Sapir, Evgenia Volinsky, Astar Lazmi-Hailu, Raphael Gorodetsky

human fetal placental stromal cells f-hPSC hair regrowth hair follicle density skin rigidity radiation-induced skin injuries

TLDR Human fetal placental stromal cell injections speed up healing and improve skin and hair recovery after radiation damage.

The study investigated the effects of isolated human fetal placental stromal cells (f-hPSC) on severe skin damage caused by high-dose irradiation in mice. Mice treated with f-hPSC showed significantly improved skin condition, reduced lesion severity, and promoted hair regrowth compared to untreated irradiated controls. Histological analysis revealed higher hair follicle density and reduced skin rigidity in f-hPSC treated mice. These findings suggest that f-hPSC could be a promising treatment for radiation-induced skin injuries.

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