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Myc activation reduces skin stem cells by affecting cell adhesion.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Spermidine may help reduce hair loss and deserves further testing as a treatment.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

Boosting β-catenin signaling in certain skin cells can enhance hair growth.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

Growth hormone levels affect hair growth and loss, with too much causing excess hair and too little leading to hair loss.

Dexpanthenol helps human hair follicle cells grow by preventing aging and death, and by supporting growth signals.

Laminin 332 is essential for normal skin cell behavior and structure.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

Hormone levels in hair change during pregnancy, with progesterone increasing significantly compared to non-pregnant women.

Gut microbes significantly affect brain steroid levels.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Tectoridin helps human hair cells grow and makes mouse hair longer, suggesting it could treat hair loss.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Enzymes called PADIs play a key role in hair growth and loss.

Managing diabetes can lead to eating disorders, and eating disorders can make diabetes harder to control.

Melatonin may help hair growth by affecting cell growth and hair-related signaling pathways.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Limonin from young citrus fruits may help with hair growth by affecting cell growth and hair cycle pathways.