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Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Activating ER-β, not ER-α, improves skin cell growth and wound healing.

The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Long-term estrogen therapy in postmenopausal women can improve certain health markers, hair loss is common regardless of hormone use, stopping estrogen doesn't increase breast cancer risk, smoking does, and a balanced BMI is linked to lower mortality.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

New treatments for male hypogonadism are effective and should be personalized.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Menopause worsens skin, hair, and nails, affecting self-esteem and quality of life.

Some breast cancer patients on hormone therapy experience hair loss, and treatments like certain topical inhibitors and supplements may help without harming their cancer prognosis.

Red clover extract improved hair, skin, mood, sleep, and tiredness in postmenopausal women.

Hormone therapy for breast cancer often leads to sexual issues like vaginal dryness and decreased libido.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Late-onset alopecia areata in Taiwanese patients is more common in women, usually starts at age 57, often involves less than 10% hair loss, and may have a minimal link to thyroid issues.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

The most common skin problems in perimenopausal women in South India are infections, eczemas, and acne, possibly worsened by external factors and lifestyle practices.

Erosive pustular dermatosis is a rare skin disease that's hard to treat and affects the scalp or legs.

Honey and bee pollen can help reduce menopausal symptoms in breast cancer patients.