150 citations
,
April 2013 in “Dermato-endocrinology” This review discusses the effects of estrogen on skin aging and highlights potential therapies, but reports no new clinical findings.
149 citations
,
January 2011 in “Nature reviews. Urology” Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.
137 citations
,
June 2005 in “Climacteric” This review indicates that estrogen loss during menopause significantly impacts skin health, while estrogen treatment may increase skin collagen, thickness, and elasticity, though effects on other skin characteristics are inconsistent.
130 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that estrogen receptor beta, not alpha, is the main mediator of estrogen action in human skin and hair follicles, suggesting a distinct role in these tissues.
120 citations
,
April 2019 in “The Journal of clinical investigation/The journal of clinical investigation” This review discusses the roles estrogens play in males and androgens in females, challenging the traditional view of strictly "male" and "female" hormones, but it does not report new experimental findings.