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    Glossary Estrogenic

    substances mimic or enhance estrogen's effects in the body

    "Estrogenic" refers to substances or activities that mimic or enhance the effects of estrogen, a primary female sex hormone. These effects can influence various biological processes, including the regulation of the menstrual cycle, reproductive system, and secondary sexual characteristics. In the context of hair and alopecia, estrogenic compounds can impact hair growth and loss patterns, often promoting hair growth and reducing hair thinning.

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    1. Estrogen and androgen signaling in the pathogenesis of BPH Nature reviews. Urology · 2011 · 149 citations
    2. Estrogens and the skin Climacteric · 2005 · 137 citations
    3. The Distribution of Estrogen Receptor β Is Distinct to That of Estrogen Receptor α and the Androgen Receptor in Human Skin and the Pilosebaceous Unit Journal of Investigative Dermatology Symposium Proceedings · 2003 · 130 citations
    4. Impact of estrogens in males and androgens in females 2019 · 120 citations
    5. Effect of estrogens on skin aging and the potential role of selective estrogen receptor modulators Climacteric · 2007 · 67 citations
    6. The Modulation of Aromatase and Estrogen Receptor Alpha in Cultured Human Dermal Papilla Cells by Dexamethasone: A Novel Mechanism for Selective Action of Estrogen via Estrogen Receptor Beta? Journal of Investigative Dermatology · 2006 · 65 citations
    7. Specific morphogenetic events in mouse external genitalia sex differentiation are responsive/dependent upon androgens and/or estrogens Differentiation · 2012 · 51 citations
    8. Aromatase-independent testosterone conversion into estrogenic steroids is inhibited by a 5α-reductase inhibitor The Journal of Steroid Biochemistry and Molecular Biology · 2005 · 44 citations
    9. 17β-Estradiol Inhibits Wound Healing in Male Mice via Estrogen Receptor-α American Journal Of Pathology · 2010 · 38 citations
    10. Estrogenic Potential of 2-Alkyl-4-(thio)chromenone 6-<i>O</i>-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase Journal of Medicinal Chemistry · 2003 · 37 citations
    11. Studies of the components of an oral contraceptive agent in albino rats. I. Estrogenic component Journal of Toxicology and Environmental Health · 1980 · 36 citations
    12. Neo-synthesis of estrogenic or androgenic neurosteroids determine whether long-term potentiation or depression is induced in hippocampus of male rat Frontiers in Cellular Neuroscience · 2015 · 32 citations
    13. Differing responses of human follicular and nonfollicular scalp cells in an in vitro wound healing assay: Effects of estrogen on vascular endothelial growth factor secretion Wound Repair and Regeneration · 2008 · 30 citations
    14. Synaptic Long-Term Potentiation and Depression in the Rat Medial Vestibular Nuclei Depend on Neural Activation of Estrogenic and Androgenic Signals PLoS ONE · 2013 · 25 citations
    15. Testosterone Prevents Cutaneous Ischemia and Necrosis in Males Through Complementary Estrogenic and Androgenic Actions Arteriosclerosis, thrombosis, and vascular biology · 2017 · 12 citations
    16. Mechanism of action of bolandiol (19-nortestosterone-3β,17β-diol), a unique anabolic steroid with androgenic, estrogenic, and progestational activities 2009 · 11 citations
    17. Research Brief: Self-Reports of a Constellation of Persistent Antiandrogenic, Estrogenic, Physical, and Psychological Effects of Finasteride Usage Among Men American Journal of Men's Health · 2018 · 9 citations
    18. Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells International Journal of Molecular Sciences · 2022 · 8 citations
    19. Minoxidil May be a Partial Agonist of Estrogen Receptor Alpha microPublication · 2026
    20. Differences in male and female pattern hair loss based on androgens, estrogen, iron, vitamin D, lipid metabolism, and genetic regulation Journal of Cutaneous and Aesthetic Surgery · 2026
    21. Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework Frontiers in Toxicology · 2025
    22. Early androgen activity after birth determines the hypothalamic expression of androgen and estrogen receptors in adulthood in female but not in male rats Reproductive Biology and Endocrinology · 2025
    23. In-silico screening of potential anti-androgenic and anti-estrogenic phytocompounds from Saraca asoca for polycystic ovary syndrome treatment Journal of Applied Pharmaceutical Science · 2024
    24. Complex Extract of Polygonatum sibiricum and Nelumbinis semen Improves Menopause Symptoms via Regulation of Estrogen Receptor Beta in an Ovariectomized Rat Model Nutrients · 2023
    25. Estrogens 2022
    26. Biology of estrogens in skin: implications for skin aging Experimental Dermatology · 2005 · 187 citations
    27. The Hair Follicle as an Estrogen Target and Source Endocrine Reviews · 2006 · 159 citations
    28. The role of estrogen in cutaneous ageing and repair Maturitas · 2017 · 158 citations
    29. An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation. Proceedings of the National Academy of Sciences of the United States of America · 1996 · 154 citations
    30. Estrogens and aging skin Dermato-endocrinology · 2013 · 150 citations