June 2025 in “Natural Product Communications” This study successfully synthesized novel cercidin analogues from Cercidophyllum japonicum, confirming their structure via NMR data. The researchers suggest these compounds could facilitate future antibiotic development by advancing structure-activity-relationship studies.
98 citations
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December 2015 in “The Journal of Cell Biology” In this study, researchers found that the absence of type I or type II keratins in mice leads to severe skin barrier defects, highlighting keratins' crucial role in epidermal structure and function.
57 citations
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December 2012 in “Molecules” This study found that mahanimbicine and a crude extract of Murraya koenigii may enhance wound healing in rats by promoting faster wound contraction and higher collagen deposition.
49 citations
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January 2017 in “Oxidative Medicine and Cellular Longevity” In this study, the alcoholic extract of Eclipta alba demonstrated significant anticancer activity in vitro by inducing apoptosis in breast cancer cell lines and showed strong antioxidant properties.
45 citations
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May 2022 in “Biomedicines” This review discusses using human follicular fluid in metabolomic analysis as a diagnostic tool and predictor of success in assisted reproductive technology for PCOS patients, reporting no new results.
29 citations
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April 2019 in “Acta neuropathologica communications” This study found that β-sitosterol, a brain-penetrable phytosterol, reduced melanoma cell growth and brain metastasis formation by interfering with mitochondrial respiration, suggesting its potential as an adjuvant therapy to BRAF inhibitors for patients with melanoma brain metastases.
24 citations
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November 2015 in “International Journal of Cosmetic Science” This study demonstrated that oxidative stress contributes to dandruff, and using a potentiated ZPT shampoo improves scalp and hair condition by reducing oxidative stress.
10 citations
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January 2025 in “Biomaterials Science” This study found that a multifunctional hydrogel dressing enriched with Cu-MOF and tannic acid significantly improved full-thickness wound healing in rats, reducing the wound area to only 1.6% and promoting re-epithelialization, neovascularization, and hair follicle formation.
9 citations
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February 2024 in “mBio” This study found that biliverdin beta and delta, metabolites of heme, play a critical role in Pseudomonas aeruginosa iron acquisition and cooperative behaviors, which are crucial for the bacterium's long-term infection in cystic fibrosis patients, suggesting potential targets for new therapies.
8 citations
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February 2022 in “Molecules” This study found that Asparagus racemosus root extract significantly reduced facial sebum production and pore size in male volunteers, suggesting potential application as an anti-sebum ingredient in cosmetics.
7 citations
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September 2022 in “Communications biology” This research found that Leydig cells significantly rely on synthesizing omega-6 HUFAs to support male steroid hormone production, highlighting a new role for these fatty acids in the male reproductive system.
7 citations
,
January 2022 in “Scientific Reports” This study found that Acanthus ebracteatus extract and verbascoside induced dermal papilla cell proliferation and reduced inflammatory cytokine release in vitro, suggesting potential for anti-hair loss applications.
6 citations
,
September 2024 in “Plant Cell & Environment” This study found that in Arabidopsis root hairs, mild chitosan treatment triggered callose deposition and slowed growth, while a higher concentration inhibited growth without callose deposition, indicating different responses based on chitosan concentration.
5 citations
,
May 2025 in “Chemical and Biological Technologies in Agriculture” This study found that purified humic acids from oxidized coal enhance plant growth by modulating oxidative stress and influencing photobiological processes, with improved root growth and enzyme activity linked to antioxidant and pro-oxidant properties.
5 citations
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May 2022 in “Biomedicines” This study found that the green alga Botryococcus terribilis and its novel compounds significantly promoted hair growth marker gene expression in hair follicle dermal papilla cells without cytotoxic effects.
4 citations
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October 2025 in “Molecules” This study concluded that extracts from fermented pumpkin peel and pulp, processed with Lactobacillus strains and kombucha, may serve as multifunctional cosmetic ingredients, offering antioxidant protection, anti-aging, and skin regeneration benefits by demonstrating cytoprotective effects and reducing inflammatory cytokines in cell assays.
4 citations
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December 2024 in “European Journal of Medicinal Chemistry” This study reported the development of new pyrazole-based MPC inhibitors that effectively inhibit mitochondrial pyruvate transport, showing potential as therapeutic candidates for conditions like metabolic dysfunction-associated steatohepatitis without activating PPARγ.
3 citations
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February 2025 in “Metabolites” In this study, researchers identified specific Se6OMT enzymes in *S. epigaea* involved in the cepharanthine biosynthetic pathway, providing insights into their substrate promiscuity and essential genetic components for metabolic engineering and synthetic biology applications of cepharanthine production.
3 citations
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September 2022 in “Molecules” This study found that Camellia seed cake extract may counteract DHT-induced effects in cultured dermal papilla cells, suggesting potential to prevent or alleviate androgenetic alopecia.
2 citations
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June 2021 in “Korean Journal of Food Preservation” This study found that adding red ginseng powder to string cheese before stretching the curd produced the highest sensory scores and maintained cheese hardness, suggesting it is optimal for manufacturing red ginseng string cheese.
1 citations
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January 2024 in “Pharmaceuticals” The researchers reported that dPGS-PCL as a carrier improved the penetration of tofacitinib in an ex-vivo human skin model compared to free tofacitinib, but did not show significant differences in inhibiting IL-6 and IL-8 during short incubation.
1 citations
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February 2023 in “Pharmaceutics” This article reviews cell proteomic footprinting technology and its application in improving the authentication and quality control of cell-based immunotherapeutics, without providing new clinical results.
1 citations
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August 2022 in “Frontiers in Physiology” This study suggests that finasteride may help alleviate high-fat diet-induced kidney damage in mice by reducing TMAO synthesis and regulating gut microbiota.
August 2026 in “Pharmaceutics” In this study, radiofrequency microporation significantly improved topical minoxidil delivery and hair regrowth in a mouse model of androgenetic alopecia, with minimal systemic exposure compared to oral administration, suggesting it could be a promising needle-free option for topical therapy.
June 2026 in “Nature Communications” This study found that in stretch-mediated tissue expansion, fibroblasts adopt an embryonic-like, low-collagen state that enhances epidermal stem cell renewal, supporting coordinated skin expansion crucial for reconstructive surgeries.
The researchers reported that PPARβ/δ may influence the yak hair follicle cycle by modulating lipid metabolism in dermal papilla cells, with varying expression during different hair growth phases, affecting both lipid content and cell proliferation.
September 2025 in “Indian Journal of Psychiatry” This study found that individuals taking valproate had a higher incidence of hair loss and reported an association between valproate levels, reduced biotinidase activity, and hair loss, compared to a control group.
August 2025 in “Current Issues in Molecular Biology” This study demonstrated that Periplaneta americana extract significantly promoted hair regeneration in depilated mice by enhancing superoxide dismutase activity, upregulating vascular endothelial growth factor, modulating the FOXO/PI3K/AKT pathway, and restoring skin microbiome balance, suggesting its potential as a novel therapeutic candidate for alopecia.
This study found that teak leaf extract can be effective in promoting hair growth in males with androgenic alopecia; however, significant variability in steroid 5-alpha reductase inhibitory activity among samples from different geographic origins means quality control is important for consistent therapeutic potential.
May 2025 in “International Journal of Cosmetic Science” In this study, researchers found that a shampoo containing caffeine and adenosine significantly altered the scalp microbiome and lipidome in subjects with hair loss over 12 weeks, which may suggest a role for these compounds in enhancing anti-hair loss processes.