Anti-Aging, Anti-Inflammatory, and Cytoprotective Properties of Lactobacillus- and Kombucha-Fermented Cucurbita Pepo L. Peel and Pulp Extracts with Prototype Skin Toner Development

    October 2025 in “ Molecules ”
    Aleksandra Ziemlewska, Zofia Nizioł‐Łukaszewska, Martyna Zagórska-Dziok … Ireneusz Sowa
    Studysummary This study concluded that extracts from fermented pumpkin peel and pulp, processed with Lactobacillus strains and kombucha, may serve as multifunctional cosmetic ingredients, offering antioxidant protection, anti-aging, and skin regeneration benefits by demonstrating cytoprotective effects and reducing inflammatory cytokines in cell assays.
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    Research cited in this study 2

    1. Beneficial Effects of Pumpkin Seed Oil as a Topical Hair Growth Promoting Agent in a Mice Model DOAJ (DOAJ: Directory of Open Access Journals) · 2019
    2. Effect of Pumpkin Seed Oil on Hair Growth in Men with Androgenetic Alopecia: A Randomized, Double-Blind, Placebo-Controlled Trial Evidence-based Complementary and Alternative Medicine · 2014