Beneficial Effects of Pumpkin Seed Oil as a Topical Hair Growth Promoting Agent in a Mice Model

    Valiollah Hajhashemi, Parvin Rajabi, M Mardani
    Image of study
    TLDR Pumpkin seed oil may help hair grow and could be an alternative treatment for male hair loss.
    In 2019, a study was conducted on male Swiss mice to evaluate the hair growth promoting activity of pumpkin seed oil (PSO). The mice were treated with testosterone, PSO, and minoxidil for three weeks. The results showed that testosterone prevented hair growth, while PSO increased hair growth. After three weeks, the percentage of hair follicles in the active growth phase was 44.4±15 for the testosterone-treated group, 75±5.3 for the PSO group, and 91.3±4.4 for the minoxidil group. The study concluded that PSO promoted hair growth and could be a promising alternative for treating male pattern alopecia. The exact mechanism of PSO's effect was unclear and required further investigation.
    Discuss this study in the Community →

    Research cited in this study

    11 / 11 results

    Related Community Posts Join

    6 / 280 results

      community Natural Remedies: Polyphenols and Hair Loss

       19 upvotes 5 years ago
      Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

      community Hairloss is mentally exhausting

      in Chat  25 upvotes 3 years ago
      The conversation is about the mental toll of hair loss and seeking alternatives to finasteride. Suggestions include using minoxidil, considering pumpkin seed oil, and possibly seeking counseling for body dysmorphic disorder.

      community RU58841 in Pumpkin Seed Oil (PSO)

      in Treatment  2 upvotes 5 months ago
      A user is seeing good results with RU58841 for hair loss, noting reduced shedding and thicker hair. They plan to use pumpkin seed oil as a solvent to avoid water content, which they believe reduces the effectiveness of anti-androgens.

      community Why Didn't the Pumkin Seed Oil Study Get More Attention?

      in Question  70 upvotes 5 years ago
      Pumpkin seed oil showed a 40% increase in hair count, but its effectiveness is questioned due to other ingredients in the supplement. Users discuss its potential compared to finasteride, with some expressing skepticism and others showing interest.

      community Best way to include peppermint oil into the routine?

      in Treatment  7 upvotes 3 years ago
      The conversation discusses incorporating peppermint oil into a hair loss treatment routine alongside minoxidil and possibly considering other second line options before using peppermint oil. Some people apply peppermint oil after minoxidil's absorption period or use shampoos containing peppermint oil.

    Similar Research

    5 / 150 results