TLDR Minoxidil solution applied on skin can effectively promote hair growth and increase hair thickness in male mice.
The study conducted 12 years ago aimed to assess the efficacy of topical minoxidil solution in promoting hair growth using a mouse model. 45 albino-Webster male mice were divided into two groups: a control group and a group treated with 5% topical minoxidil solution. After 21 days, significant hair growth was observed in the minoxidil-treated group compared to the control group. There was also a significant increase in the diameter of hair follicles, but no significant increase in the number of hair follicles. The study concluded that topical minoxidil solution can efficiently promote hair growth and increase the diameter of hair follicles. The concentration of certain hormones (17β-Estradiol, Free Testosterone, and Progesterone) were also measured after the treatment period, but no significant difference was found between the control and treatment groups.
370 citations,
September 1999 in “The New England Journal of Medicine” Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.
59 citations,
February 1998 in “Chemico-Biological Interactions” Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.
227 citations,
January 1998 in “Journal of Endocrinology” Cells from balding scalps have more androgen receptors than cells from non-balding scalps.
32 citations,
January 1994 in “Skin Pharmacology and Physiology” Minoxidil helps hair growth by activating enzymes in hair follicles.
166 citations,
November 1990 in “Journal of Investigative Dermatology” Minoxidil sulfate stimulates hair growth.
68 citations,
September 1990 in “Biochemical Pharmacology” Minoxidil activates hair growth by being sulfated by P-PST in the human liver.
138 citations,
August 1985 in “Journal of The American Academy of Dermatology” Minoxidil promotes hair growth in male pattern baldness.
137 citations,
May 1984 in “Journal of Investigative Dermatology” Minoxidil increases blood flow in balding scalps, possibly reversing hair loss.
10 citations,
January 2021 in “Journal of Ginseng Research” Red ginseng oil may help grow hair and protect skin from UVC light.
