Identification and Characterization of Two Se6OMTs from Stephania Epigaea Offer Novel Insights into the Biosynthetic Pathway of Cepharanthine

    February 2025 in “ Metabolites
    Jingyi Gan, Wenlong Shi, Qishuang Li, Xinyi Li, Xingyu Zhao, Julian W. Tang, Ying Ma, Jian Wang, Shukun Gong, Xiaohui Ma, Juan Guo
    Studysummary In this study, researchers identified specific Se6OMT enzymes in *S. epigaea* involved in the cepharanthine biosynthetic pathway, providing insights into their substrate promiscuity and essential genetic components for metabolic engineering and synthetic biology applications of cepharanthine production.
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