19 citations
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June 2008 in “Journal of Investigative Dermatology” This study found that transgenic mice with expression of HPV16 E6/E7 oncogenes showed improved ear tissue regeneration, including hair follicles and cartilage, without tumor formation.
22 citations
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November 2016 in “Indian Journal of Pharmaceutical Education and Research” This study found that ethanolic leaves extract of Hibiscus rosa-sinensis L. exhibited strong antioxidant activity and enhanced wound healing properties in mice, showing reasonable safety in toxicological evaluations without severe alterations.
1 citations
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January 2023 in “Journal of research in pharmacy” This study found that the methanolic extract of Carduus adpressus exhibited strong antibacterial, antioxidant, and wound-healing activities, suggesting its potential use in developing wound-healing agents.
September 2024 in “Journal of the Pakistan Medical Association” This study found that helium non-equilibrium atmospheric pressure plasma jet therapy accelerated wound healing in both diabetic and non-diabetic dogs, promoting wound closure and histological improvements like epithelization and collagen deposition compared to untreated wounds.
18 citations
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January 2024 in “Regenerative Biomaterials” This study developed and tested a new injectable hydrogel for chronic diabetic wounds, reporting significant improvements in wound healing through enhanced angiogenesis, epithelization, and reduction of inflammation and infection in animal models.
10 citations
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January 2024 in “Burns & Trauma” This meta-analysis found that ADSC-Exo therapy can enhance healing in both general and diabetic wounds by promoting neovascularization, improving epithelization and collagen fiber deposition, and reducing scar formation, suggesting significant potential for clinical and research applications.
7 citations
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March 2024 in “Veterinary Medicine and Science” In this study, eight dogs with naturally occurring skin wounds were treated with autologous platelet-rich fibrin therapy, which significantly promoted wound healing and tissue regeneration without using additional medications, leading to promising outcomes and minimal scarring.
1 citations
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October 2018 in “PubMed” In a mouse model of infected burns, this study found that treatment with recombinant fusion peptide EK significantly decreased Pseudomonas aeruginosa colony count and improved wound healing rates compared to controls.
1 citations
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March 2001 in “JOURNAL OF THE KYORIN MEDICAL SOCIETY” In this study, a collagen sponge with isogenic fibroblasts did not enhance skin graft survival or wound healing in rats, but it did promote re-epithelization, potentially inducing epithelial inclusion cysts.
June 2024 in “International journal of biological macromolecules” This study reports that beta-glucan hybrid hydrogels, reinforced with laponite nanoclay, showed promising results in rat models for managing hemorrhage and diabetic wound healing by enhancing hemostasis, reducing inflammation, and promoting faster wound closure and tissue regeneration.
January 2024 in “Wiadomości Lekarskie” In this study, wounds treated with a combination of 0.02% Decamethoxine and Blastomunil showed enhanced healing and epithelization by the 14th day, leveraging the immunomodulatory and antimicrobial properties of the agents.
January 2013 in “Zhongguo bingli shengli zazhi” In this rat study, Coriaria sinica Maxim extract significantly improved burn wound healing by enhancing epithelial growth and promoting hair regrowth, possibly through early-stage protein and mRNA expression changes.
56 citations
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November 2022 in “Biomolecules” This review explores the role of macrophage subsets in adult cutaneous wound healing and emphasizes their potential for therapeutic targeting, but reports no new experimental results.
January 2018 in “Bradford Scholars (University of Bradford)” This study found that SWI/SNF complexes, especially the ATPase BRG1, are crucial for keratinocyte migration in human wound healing but do not affect hair growth in short-term hair follicle cultures.
64 citations
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August 2007 in “Artificial Organs” This study found that PHBV cocultured with epithelial and dermal cells might enhance early-stage wound healing by promoting wound closure and re-epithelization more effectively than PHBV/collagen.
36 citations
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April 2013 in “Cell and Tissue Research” Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.
19 citations
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January 2023 in “Frontiers in Bioengineering and Biotechnology” This review discusses the therapeutic potential of mesenchymal stem cell-derived small extracellular vesicles for chronic wound treatment and reports no new clinical results, emphasizing the need for further research on their large-scale production and engineering.
7 citations
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December 2022 in “Frontiers in Bioengineering and Biotechnology” This review discusses the role of extracellular vesicles as therapeutic agents for wound healing and highlights the need for further research into their clinical applications.
6 citations
,
December 2022 in “Colloids and Surfaces B: Biointerfaces” This study reported that a novel bilayer wound dressing made from PLCL nanofibers and keratin hydrogel, loaded with FGF-2, promoted skin healing and showed potential for use in skin tissue engineering.
3 citations
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April 2022 in “Veterinary world/Veterinary World” In this study, mesenchymal stem cell-conditioned medium gel significantly improved wound healing and accelerated hair growth in rats with third-degree burns compared to a placebo, silver sulfadiazine, or no treatment.
2 citations
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December 2022 in “Bio-Design and Manufacturing” This study demonstrates that the newly developed portable reflectance confocal microscope (PRCM) offers real-time, noninvasive monitoring of wound healing processes by visualizing skin morphology in both mice and humans.
This study reported that hydrogels created from keratins extracted from human hair exhibit antibacterial properties and enhance tissue regeneration, suggesting their potential use in full-thickness skin repair, as demonstrated by increased collagen production and improved healing in vivo.
December 2024 in “ACS Applied Materials & Interfaces” In this study, dynamic hyaluronic acid hydrogels with properties like injectability and controlled degradation were developed to enhance healing and remodeling of diabetic wounds, achieving effects such as inflammation reduction, increased angiogenesis, and neovascularization, leading to complete wound healing.
November 2023 in “Advanced functional materials” This study suggests that inorganic magnesium silicate sprays can improve burn wound repair and promote regeneration of skin appendages, showing superior results compared to commercial wound healing products in animal models.
May 2021 in “ThinkTech (Texas Tech University)” In this study, BlastX wound gel did not interfere with wound healing in both uninfected and S. aureus infected murine wounds, and it may enhance healing in uninfected conditions.
April 2018 in “Journal of Investigative Dermatology” This study found that Basonuclin 1 knockdown in human primary keratinocytes significantly reduces cell proliferation and affects migration, indicating its role in coordinating the re-epithelization phase of wound healing.
20 citations
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June 2020 in “Stem Cell Research & Therapy” This study found that treating acute and chronic canine skin wounds with adipose-derived mesenchymal stem cells significantly improved healing and reduced inflammation, suggesting potential benefits for human wound care.
1 citations
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July 2025 in “Methods and Protocols” This study supports the use of the chicken chorioallantoic membrane as an effective pre-clinical model for burn wound research and the screening of new therapeutic agents.
July 2024 in “Journal of Investigative Dermatology” Combining certain treatments, including FOL005, may improve healing of difficult wounds.
August 2010 in “The Journal of Dermatology” The document concludes that low-dose acne treatment is most suitable for moderate acne, with high patient satisfaction and low relapse rates.