130 citations,
March 2014 in “Proceedings of the National Academy of Sciences of the United States of America” Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.
41 citations,
April 2019 in “PLOS genetics” CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
23 citations,
November 2018 in “npj Regenerative Medicine” Healing of heart and skin wounds in animals are similar.
6 citations,
August 2022 in “Science immunology” Foxn1 gene regulation is crucial for thymus development but not for hair growth.
5 citations,
January 2023 in “Cell proliferation” Chick embryo extract helps rat hair follicle stem cells potentially turn into Schwann cells, important for the nervous system.
3 citations,
July 2023 in “Biomolecules” B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.
1 citations,
October 2022 in “Biomedicines” Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.
1 citations,
December 2023 in “Life” PRP helps skin heal, possibly through special cells called telocytes.
March 2024 in “Frontiers in Endocrinology” The study found that alopecia areata and hypothyroidism increase the risk of each other, but androgenetic alopecia and hypothyroidism do not.
July 2023 in “The Journal of Clinical Endocrinology and Metabolism” Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.
February 2023 in “Frontiers in Endocrinology” Too much male hormone in mothers can negatively affect the sexual behavior of both male and female baby mice.
October 2022 in “Biomedicines” Finasteride in male rats causes liver and metabolic issues in their offspring.
1 citations,
September 2019 in “Practica medicală” Hair loss is linked to heart disease and metabolic syndrome, and while current treatments vary in effectiveness, more research is needed for better solutions.
179 citations,
July 2016 in “Nature Reviews Molecular Cell Biology” Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
48 citations,
September 2011 in “British Journal of Dermatology” Epigenetic changes in blood cells may contribute to alopecia areata.
19 citations,
October 2017 in “The FASEB Journal” Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.
5 citations,
September 2015 in “PubMed” Epigenetic changes are crucial for stem cell behavior in skin wound healing and their disruption may lead to cancer.
4 citations,
February 2019 in “Journal of Cutaneous Pathology” The marker 5-hmC changes in hair follicle stem cells when they start to grow.
4 citations,
January 2013 in “European Journal of Dermatology” Epigenetic differences affect hair loss in identical Japanese male twins.
3 citations,
October 2021 in “Indian Journal of Plastic Surgery” Pattern hair loss is mainly caused by genetics and hormones, with limited effective treatments available.
2 citations,
June 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Epigenetic factors play a crucial role in skin health and disease.
1 citations,
January 2021 in “Vide Leaf, Hyderabad eBooks” Altered DNA methylation may be a marker for Polycystic Ovary Syndrome.
1 citations,
July 2011 in “Hair transplant forum international” Finasteride may cause changes in dopamine-related genes, possibly leading to post-finasteride syndrome.
November 2023 in “Magna Scientia Advanced Research and Reviews” Trazodone might help reverse post finasteride syndrome.
October 2023 in “Cell & bioscience” A special gene region controls the re-emergence of a primitive wool type in Merino sheep, improving their wool yield and adaptability.
Finasteride may help treat childhood brain tumors by activating certain genes.
Finasteride may help reduce COVID-19 infection by altering a key gene.
Both changes in genes and environmental factors like diet and toxins can significantly affect the growth of skin appendages like hair, but how these factors interact is still unclear.
April 2020 in “The FASEB Journal” Finasteride may cause lasting sexual issues by altering specific genes in human cells.