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    Glossary Epidermal Differentiation

    process where skin cells mature to form protective barrier

    Epidermal differentiation is the process by which cells in the outermost layer of the skin, called the epidermis, mature and change to form a protective barrier. This involves the transformation of basal cells into specialized cells like keratinocytes, which produce keratin, a protein that helps protect the skin from environmental damage. This process is crucial for maintaining skin integrity and function.

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    1. Retinoic Acid-Induced Epidermal Transdifferentiation in Skin Journal of developmental biology · 2014 · 1 citations
    2. Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals Proceedings of the National Academy of Sciences · 2005 · 130 citations
    3. Transdifferentiation of corneal epithelium: evidence for a linkage between the segregation of epidermal stem cells and the induction of hair follicles during embryogenesis. The International Journal of Developmental Biology · 2004 · 55 citations
    4. P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression Stem Cell Research & Therapy · 2016 · 24 citations
    5. Tgm2/Gh, Gbx1 and TGF-beta are involved in retinoic acid-induced transdifferentiation from epidermis to mucosal epithelium The International Journal of Developmental Biology · 2011 · 14 citations
    6. Epidermal stem cells: an update on their potential in regenerative medicine Expert opinion on biological therapy · 2013 · 9 citations
    7. Manipulation of stem cell proliferation and lineage commitment:visualisation of label-retaining cells in wholemounts of mouse epidermis Development · 2003 · 421 citations
    8. <i>In vivo</i> imaging of mammary epithelial cell dynamics in response to lineage-biased Wnt/β-catenin activation bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 1 citations
    9. Label Retaining Cells (LRCs) with Myoepithelial Characteristic from the Proximal Acinar Region Define Stem Cells in the Sweat Gland PLoS ONE · 2013 · 36 citations
    10. Corneal Limbal Microenvironment Can Induce Transdifferentiation of Hair Follicle Stem Cells into Corneal Epithelial-like Cells Stem Cells · 2008 · 162 citations
    11. Toward Elucidating Epigenetic and Metabolic Regulation of Stem Cell Lineage Plasticity in Skin Aging Frontiers in Cell and Developmental Biology · 2022 · 7 citations
    12. Role of  -catenin in Epidermal Stem Cell Expansion, Lineage Selection, and Cancer Cold Spring Harbor Symposia on Quantitative Biology · 2008 · 61 citations
    13. Transplantation of bone-marrow-derived mesenchymal and epidermal stem cells contribute to wound healing with different regenerative features Cell and Tissue Research · 2013 · 36 citations
    14. Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1 Development · 2010 · 34 citations
    15. Anti-aging Properties of Conditioned Media of Epidermal Progenitor Cells Derived from Mesenchymal Stem Cells Dermatology and Therapy · 2018 · 26 citations
    16. Dermal-epidermal interactions—follicle-derived cell populations in the study of hair-growth mechanisms 1993 · 19 citations
    17. Upregulation of interfollicular epidermal and hair infundibulum β-catenin expression in Gsdma3 mutant mice Acta histochemica · 2012 · 11 citations
    18. Regenerative Medicine of Epidermal Structures Elsevier eBooks · 2012
    19. DMBA/TPA Treatment Is Necessary for BCC Formation from Patched Deficient Epidermal Cells in Ptch flox/flox CD4Cre +/− Mice Journal of Investigative Dermatology · 2014 · 11 citations
    20. Protective Mechanism of Adipose-Derived Stem Cells in Remodelling of the Skin Stem Cell Niche During Photoaging Cellular Physiology and Biochemistry · 2018 · 13 citations
    21. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000 · 1010 citations
    22. Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin Genes & Development · 2001 · 555 citations
    23. Epidermal Notch signalling: differentiation, cancer and adhesion Current opinion in cell biology · 2008 · 253 citations
    24. Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells Journal of Investigative Dermatology · 2005 · 205 citations
    25. Morpho-Regulation of Ectodermal Organs ˜The œAmerican journal of pathology · 2004 · 131 citations
    26. Epidermal Stem Cells do not Communicate Through Gap Junctions Journal of Investigative Dermatology · 2002 · 73 citations
    27. Hair matrix germinative epidermal cells confer follicle-inducing capabilities on dermal sheath and high passage papilla cells Development · 1996 · 61 citations
    28. The Role of Stem Cells in Cutaneous Wound Healing: What Do We Really Know? Plastic and Reconstructive Surgery · 2011 · 43 citations
    29. Epigenetic control of skin and hair regeneration after wounding Experimental Dermatology · 2014 · 36 citations
    30. Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence Nature Communications · 2020 · 8 citations