TLDR Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.
The document reviewed various pre-clinical studies on cell-based therapies for treating Limbal Stem Cell Deficiency (LSCD), highlighting the potential of different stem cell sources such as epidermal stem cells, hair follicle-derived stem cells, and bone marrow-derived mesenchymal stem cells. These studies, conducted on animal models, showed promising results in corneal reconstruction with varying degrees of success and minimal complications. The review emphasized the need for further research to identify the most effective cell types and methods for LSCD treatment, as well as the importance of standardized parameters in experiments to improve corneal regenerative medicine.
268 citations,
December 2003 in “Experimental Dermatology” Hair follicle cells can become fat and bone cells.
1010 citations,
August 2000 in “Cell” Hair follicle stem cells can form both hair follicles and skin.
136 citations,
May 2019 in “Cells” Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
55 citations,
March 2012 in “Journal of Investigative Dermatology” Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
31 citations,
August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
132 citations,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
Stem cell treatments show promise for hair loss but need more research.
