4 citations,
January 2012 in “Chemical Immunology” Some drugs, especially biologics, can cause skin reactions that look like other skin diseases, and stopping the drug usually helps clear up these reactions.
3 citations,
February 2015 in “Mechanisms of development” Hormones and stretching both needed for nipple area skin growth in mice.
1 citations,
May 2023 in “PubMed” A certain type of skin cell, marked by EGFR, produces a lot of IGF1 and helps hair follicles grow back faster.
1 citations,
October 2022 in “JCI insight” Deleting the BRD4 protein in certain skin cells causes hair loss and skin inflammation.
1 citations,
June 2016 in “FEBS open bio” Fish oil increased cell growth and macrophages in the skin but didn't affect COX-2 expression.
January 2020 in “International journal of scientific research” Dermoscopy shows that varying hair shaft thickness and single hair follicles are main signs of male pattern baldness, especially in the fronto-temporal region.
January 2018 in “Georg Thieme Verlag eBooks” Hair transplantation is a surgical procedure to move hair to bald areas, requires good donor hair, and results show in about a year.
February 2010 in “Journal of The American Academy of Dermatology” Mimicking growth factors in a topical solution can prolong hair growth phase and reduce hair loss without side effects.
231 citations,
October 1999 in “Journal of Clinical Investigation” Activating the Sonic hedgehog gene in mice can start the hair growth phase.
163 citations,
March 2012 in “BMC biology” Stem cell niches support, regulate, and coordinate stem cell functions.
148 citations,
October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice without the vitamin D receptor are more prone to UV-induced skin tumors.
135 citations,
December 2006 in “PLoS Medicine” Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.
133 citations,
May 2016 in “Cell Host & Microbe” Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
92 citations,
April 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” Nonpalmoplantar skin cells can be made to express keratin 9 by interacting with palmoplantar fibroblasts.
48 citations,
March 2010 in “PloS one” C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.
45 citations,
September 2001 in “Journal of Investigative Dermatology” Cyclosporin A promotes hair cell growth and affects protein kinase C levels.
42 citations,
April 2012 in “Seminars in Oncology” Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.
39 citations,
September 2007 in “BMC developmental biology” Neuregulin3 affects cell development in the skin and mammary glands.
36 citations,
July 2017 in “Journal of controlled release” A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with fewer side effects.
36 citations,
June 2015 in “International journal of toxicology” Trichloroethylene causes skin inflammation in mice by increasing certain immune proteins.
28 citations,
December 2015 in “Journal of biological chemistry/The Journal of biological chemistry” Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.
27 citations,
July 1997 in “PubMed” The harlequin ichthyosis mouse mutation causes thick skin and early death, resembling a human skin disorder.
26 citations,
October 2018 in “Clinical & Translational Oncology” Spanish experts provided guidelines for treating skin side effects in cancer patients on new therapies, stressing early action and teamwork.
23 citations,
June 2012 in “Molecular Biology Reports” VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.
22 citations,
December 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” A mouse gene mutation increases the risk of skin cancer.
20 citations,
June 2014 in “Pharmaceutical research” Using both hyaluronic acid compounds together improves skin hydration and reduces wrinkles better than using one alone.
15 citations,
October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Erlotinib causes skin inflammation through IL-1, which can be reduced by anakinra.
14 citations,
December 2018 in “The American journal of pathology” Activating Nrf2 in skin cells speeds up wound healing by increasing the growth of certain stem cells.
13 citations,
April 2019 in “iScience” EGFR helps control how hair grows and forms without needing p53 protein.
11 citations,
March 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific group of skin stem cells was found to help maintain hair follicle cells.