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Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.

Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.

Fat under the skin releases HGF which helps hair grow and gain color.

Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.

ICAM-1 helps regulate hair growth cycles and skin remodeling.

sPLA2-IIE is crucial for normal hair follicle structure and skin health.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.

TGFβ signaling prevents sebaceous gland cells from producing fats.

Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.

WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

Disrupted stem cell signals in hairpoor mice cause hair loss.

Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.

DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.

sPLA2-X is crucial for normal hair growth and follicle health.

Miz1 is essential for proper hair structure and growth.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Targeted anticancer therapies in children often cause skin side effects like rash and dry skin.

Different fields of expertise must work together to better understand hair growth and create effective hair loss treatments.

Hair is important for protection, social interaction, and temperature control, and is made of a growth cycle-influenced follicle and a complex shaft.

Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.

Bmpr2 and Acvr2a receptors are crucial for hair retention and color.

Intermediate filaments are crucial for cell differentiation and stem cell function.

Enzymes called PADIs play a key role in hair growth and loss.

Exosome treatment for hair growth is promising but not FDA-approved and needs more research on safety and how it works.

Thermal spring waters and their microbes could be good for skin health and treating some skin conditions in skincare products.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.