27 citations
,
May 2006 in “Biochemical and Biophysical Research Communications” In this study, Wnt-10b was found to promote hair follicle development and hair growth in cultured mouse embryonic skin and transplanted skin in nude mice.
11 citations
,
June 2010 in “Medical Molecular Morphology” September 2023 in “Animals” In this study, researchers used proteomic and metabolomic analyses to explore hair follicle development in embryonic cashmere goats, identifying significant roles for the oxytocin signalling pathway and associated networks in this process.
15 citations
,
March 2022 in “Poultry Science” In this study, in ovo injection of CHIR-99021 promoted the morphogenesis and development of feather follicles in chick embryos by activating the Wnt/β-catenin signaling pathway.
4 citations
,
February 2024 in “Poultry Science” This study found that the miR-140-y-TCF4 axis regulates the proliferation of goose embryonic dermal fibroblast cells by affecting the Wnt signaling pathway, highlighting its role as a dynamic regulator during skin and feather follicle development.
46 citations
,
August 2022 in “Animals” This study identified key genes and miRNAs involved in feather morphogenesis in Zhedong White geese, highlighting a negative correlation between FOXO3 and miR-144-y.
71 citations
,
November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses the role of Edar signaling in hair follicle development and cycling, emphasizing its impact on cell fate, differentiation, and interactions with other pathways, but reports no new results.
10 citations
,
September 2018 in “Regenerative Medicine” This review explores the mechanism and potential applications of wound-induced hair follicle neogenesis but reports no new clinical results, highlighting the need for further research in hair regeneration therapies.
12 citations
,
December 2020 in “Archives animal breeding/Archiv für Tierzucht” This study found that EDA and EDAR are expressed throughout cashmere goat fetal development and play a critical role in hair follicle formation by influencing gene expression in fibroblasts and epithelial cells.
12 citations
,
August 2007 in “Human Molecular Genetics” This study found that Lymphotoxin-beta primarily influences periderm differentiation, impacting epidermal and hair follicle differentiation at later stages.
June 2022 in “Research Square (Research Square)” This study revealed that nestin-expressing progenitor cells capable of becoming ORS keratinocytes are present during both hair follicle development and in adult hair follicles.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that targeting the tumor stroma to promote the formation of dermal condensates may offer a novel approach to treating basal cell carcinoma.
January 2010 in “Chinese journal of clinical anatomy” This study observed that hair follicle development in C57BL/6 mice begins at fetal stage E15.5, with a rapid increase in hair follicle numbers from E17.5 to three days after birth.
43 citations
,
January 2012 in “Biological Research” This review discusses the embryonic origins and characteristics of various stem cell populations in the skin, but it provides no new experimental results.
This review examines the factors influencing the formation of lamb skin in Tan sheep, highlighting the role of follicle development and gene regulation but reports no new experimental findings.
14 citations
,
September 2001 in “Archives of Dermatological Research” This study reported that Sonic hedgehog signaling is crucial for hair follicle development, with its expression being significantly induced in normal embryonic hair germs but inhibited in certain experimental models.
25 citations
,
May 2013 in “Journal of mammary gland biology and neoplasia” This review examines the roles of Hedgehog and Gli proteins in mouse embryonic mammary development and suggests that Gli3-repressor-mediated off-state of Hedgehog signaling determines mammary fate over hair follicle fate.
193 citations
,
May 2008 in “Development” This study found that activating β-catenin signaling in embryonic epidermis promoted hair follicle characteristics at the expense of normal epidermal differentiation, leading to early pigmentation and innervation.
173 citations
,
August 2015 in “Developmental cell” This study characterizes gene expression patterns in embryonic hair follicle progenitors and their niche, identifying signaling pathways like axon guidance that may drive cellular rearrangements for hair follicle formation.
81 citations
,
September 2009 in “Birth defects research” This review discusses the mechanisms behind hair patterning during mouse embryonic development and reports no new experimental findings.
8 citations
,
January 2025 in “Journal of Investigative Dermatology” In this study, researchers analyzing human fetal skin fibroblasts found eight distinct populations with developmental stage-specific abundance, identifying markers linked to fibroblast functions in blood vessel development, dermal layers, and hair follicle maturation.
July 2008 in “VTechWorks (Virginia Tech)” This study suggests that PrPC plays a role in the differentiation of mouse embryonic stem cells during neurogenesis, impacting neural progenitor cell development.
3 citations
,
November 2018 in “Curēus” This article reviews the occurrence of ectopic sebaceous glands in hair follicle matrix during hair embryogenesis and reports no new clinical results, indicating unknown pathogenesis and clinical implications.
17 citations
,
December 2006 in “Gene Expression Patterns” This study reports that the mouse Scube3 gene is expressed in various tissues during embryonic development, including the neural tube, limb buds, developing tooth, hair follicle, and skeletal regions.
7 citations
,
December 2007 in “Poultry Science” In this study, beta-catenin expression was found to be significant in embryonic goose skin during early feather bud development, with patterns similar to Shh expression, suggesting its importance in normal development.
829 citations
,
May 2007 in “Nature” Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
May 2007 in “Science's STKE” This study found that modulating Wnt signaling can promote new hair follicle regeneration in adult mouse skin wounds, suggesting potential treatment strategies for scarring and alopecia.
77 citations
,
April 1968 in “Development” This study found that excess vitamin A in organotypic cultures of embryonic mouse skin led to abnormal hair follicle development and glandular metaplasia, unlike in untreated controls that showed normal differentiation.
5 citations
,
January 2022 in “PloS one” This study found that lineage-restricted loss of p63 in murine thymic epithelial cells resulted in severe thymic hypoplasia and absence of hair follicles, indicating p63's critical role in thymic and hair follicle development.
August 2018 in “Journal of Investigative Dermatology” This study found that centrosomes, unlike cilia, are essential for proper epidermal and hair follicle development in mice, with these effects being dependent on the presence of p53.