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    Glossary EDAR gene

    provides instructions for a protein crucial in hair development

    The EDAR gene provides instructions for making a protein that is crucial for the development of hair, teeth, and sweat glands. Mutations in this gene can lead to conditions like hypohidrotic ectodermal dysplasia, which affects these structures, resulting in sparse hair, missing teeth, and reduced ability to sweat.

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    Research 30 of 515

    1. A replication study confirmed the EDAR gene to be a major contributor to population differentiation regarding head hair thickness in Asia Human genetics · 2008 · 89 citations
    2. Combination of Transcriptomics and Proteomics Reveals Differentially Expressed Genes and Proteins in the Skin of EDAR Gene-Targeted and Wildtype Cashmere Goats Animals · 2023 · 1 citations
    3. Mutational spectrum of EDA, EDAR, EDARADD, and WNT10A genes in the largest cohort of Russian patients with hypohidrotic ectodermal dysplasia Orphanet Journal of Rare Diseases · 2026
    4. Investigation of the male pattern baldness major genetic susceptibility loci AR/EDA2R and 20p11 in female pattern hair loss British Journal of Dermatology · 2012 · 38 citations
    5. EDA and EDAR expression at different stages of hair follicle development in cashmere goats and effects on expression of related genes 2020 · 12 citations
    6. EDA2R Is Associated with Androgenetic Alopecia Journal of Investigative Dermatology · 2008 · 82 citations
    7. Fine mapping of the human <i>AR/EDA2R</i> locus in androgenetic alopecia British Journal of Dermatology · 2010 · 28 citations
    8. A Theoretical Model for the Treatment of Androgenetic Alopecia Using the STEAP3 Protein, and the Genetic Challenges of Treating AGA Health Science Reports · 2026
    9. Uncovering the genetic architecture and evolutionary roots of androgenetic alopecia in African men Human Genetics and Genomics Advances · 2025
    10. Uncovering the genetic architecture and evolutionary roots of androgenetic alopecia in African men bioRxiv (Cold Spring Harbor Laboratory) · 2024
    11. A review of genetic researches of and rogenic alopecia Int J Genet · 2016
    12. Enhanced ectodysplasin-A receptor (EDAR) signaling alters multiple fiber characteristics to produce the East Asian hair form Human mutation · 2008 · 98 citations
    13. Generation of Cashmere Goats Carrying an <i>EDAR</i> Gene Mutant Using CRISPR-Cas9-Mediated Genome Editing International Journal of Biological Sciences · 2018 · 33 citations
    14. Novel missense mutation in the EDA gene in a family affected by oligodontia 2016 · 12 citations
    15. Hair shaft structures in EDAR induced ectodermal dysplasia BMC Medical Genetics · 2015 · 5 citations
    16. Advances in the genetic understanding of hypohidrotic ectodermal dysplasia Expert opinion on orphan drugs · 2017 · 1 citations
    17. Divergent genetic mechanism leads to spiny hair in rodents bioRxiv (Cold Spring Harbor Laboratory) · 2018
    18. Genetic Mapping Of Hereditary Ectodermal Dysplasias And Hair Loss Genes 2011
    19. INDENTIFICATION OF GENES INVOLVED IN INHERITED ECTODERMAL DYSPLASIAS 2008
    20. Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis Development · 2000 · 208 citations
    21. Current Genetics in Hair Diseases InTech eBooks · 2013 · 1 citations
    22. Genetic and molecular aspects of androgenetic alopecia Indian Journal of Dermatology, Venereology and Leprology · 2018 · 24 citations
    23. Hunting the genes in male‐pattern alopecia: how important are they, how close are we and what will they tell us? Experimental Dermatology · 2016 · 46 citations
    24. Facial skin aging: an integrative analysis of genetics, epigenetics, and lifestyle factors GeroScience · 2025
    25. Involvement of the Edar Signaling in the Control of Hair Follicle Involution (Catagen) ˜The œAmerican journal of pathology · 2006 · 43 citations
    26. Genetics of Alopecia Encyclopedia of Life Sciences · 2012
    27. Comparative histomorphometric and transcriptomic analysis reveals potential genetic determinants of pelage variation between hairy and coarse-woolly sheep BMC Genomics · 2025
    28. Biology and Genetics of Hair Annual Review of Genomics and Human Genetics · 2010 · 89 citations
    29. Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development 2012 · 48 citations
    30. m6A Methylation Analysis Reveals Networks and Key Genes Underlying the Coarse and Fine Wool Traits in a Full-sib Merino Family Biology · 2022 · 9 citations