Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study introduced a reproducible human model using 3D-SeboSkin technology to study hidradenitis suppurativa, allowing better maintenance of skin integrity and replication of biomarker expression patterns compared to traditional skin cultures, suggesting its value for further research.

This study found that combining minoxidil with all-trans retinoic acid additively promoted hair growth in vitro by activating certain cell survival pathways and reducing apoptosis markers more effectively than minoxidil alone.

This study suggests that apigenin may stimulate hair growth by downregulating TGF-ß1 gene expression in human epidermal keratinocytes and promoting hair follicle elongation in a rat hair follicle culture.

This study reports that using nanogel and layer-by-layer self-assembly to encapsulate single dermal papilla cells can form cell spheroids that regenerate hair follicles successfully in a hair follicle regeneration model.

This study found that platelet-rich plasma may influence the proliferation of human hair dermal papilla cells by affecting gene expression related to the cell cycle.

This study found that applying HHORSC exosomes may enhance the hair inductivity of dermal papilla cells, potentially improving treatments for hair loss.

This laboratory study found that nonanal, a plant scent compound, may stimulate growth factors and cell proliferation in human hair follicle dermal papilla cells, suggesting a cAMP-mediated mechanism.

This study suggests that administering SH-MSCs gel might decrease IL-6 expression and increase TGF-β expression in alopecia-like rats, indicating potential for alopecia therapy.

In this study, researchers differentiated human induced pluripotent stem cells into dermal papilla-like cells and observed gene expression dynamics during five stages of dermal differentiation, demonstrating the potential of these cells to interact with epidermal cells in functional assays.

This study suggests that a specific region upstream of the TGF-β1 gene may play a key role in androgenetic alopecia by regulating gene expression in a cell-specific manner.

This study found that stem cells derived from root apical papilla in extracted wisdom teeth demonstrated the strongest potential for osteogenic differentiation compared to those from dental pulp and dental follicle.

This article reviews the use of mesenchymal stem cells and biomimetic scaffolds in regenerative medicine, highlighting promising in vitro and in vivo outcomes, but it reports no new clinical results.

This review discusses the potential of dental tissues as an alternative source of adult stem cells for regenerative medicine but reports no new experimental results, emphasizing the need for effective preservation methods.

This literature review reports that mesenchymal stem cell-derived secretome, including conditioned medium and extracellular vesicles, shows promise as an effective treatment for various diseases in animal and human in-vivo models, with ongoing clinical trials and recommendations for future research discussed.

Micrografts are useful for healing wounds, regenerating bone and periodontal tissues, and improving hair transplantation outcomes.

This study found that loss of Apc due to K14-cre-mediated gene recombination in mice led to aberrant growth in ectodermally derived squamous epithelia, implicating its critical role in specifying epithelial cell fates during embryonic development.

This review discusses the WNT signaling pathway's involvement in human diseases and highlights recent advances in WNT-related treatments, but it presents no new research findings.

This article discusses the high toxicity and potential use of thallium as a poison, highlighted by two cases of intentional thallium poisoning.

This study found that topical minoxidil modestly extended the anagen phase in mice by activating β-catenin activity in dermal papilla cells.

In this study, dermal papilla cell-derived exosomes accelerated hair follicle growth in mice, suggesting potential for treating hair loss by modulating key signaling pathways.

This study proposes the miR-22-5p-LEF1 axis as a novel pathway that may regulate hair follicle stem cell proliferation.

This review indicates that most studies reported positive effects of platelet-rich plasma injections for treating androgenic alopecia, with no major side effects, suggesting it may be a safe alternative to Minoxidil and Finasteride.

This review discusses the potential of endogenic and exogenous exosomes in dermatology and cutaneous aesthetics, highlighting their capacity to repair and rejuvenate skin tissue, but reports no new experimental results.

This review discusses the steroidogenic properties of human skin and suggests that impaired steroidogenesis may be linked to conditions like acne, rosacea, atopic dermatitis, and androgenic alopecia, but reports no new clinical results.

This review discusses potential cell sources and bioengineering strategies for regenerating hair follicles with functional cycling, reporting no new results.

This study suggests that mesenchymal stem cell-induced dermal papilla-like tissues can generate new hair follicles in mice, indicating potential for developing hair cell therapy using stem cells.

This study found that hydroxysafflor yellow A-rich Carthamus tinctorius extract promoted hair growth and gene expression linked to hair proliferation in both cell cultures and mouse models.

This study found that combining minoxidil and retinol additively promoted hair growth in vitro, enhancing Erk- and Akt-dependent pathways and preventing apoptosis in dermal papilla cells and keratinocytes.

This study found that white wax and its extract may promote hair growth in a mouse model of androgenetic alopecia by inhibiting 5α-reductase activity and increasing cell proliferation, with efficacy surpassing finasteride.

This study found that 3-Deoxysappanchalcone may stimulate hair growth in mice by promoting proliferation of hair follicle dermal papilla cells through WNT/β-catenin and STAT signaling modulation.