Nonanal Stimulates Growth Factors via Cyclic Adenosine Monophosphate (cAMP) Signaling in Human Hair Follicle Dermal Papilla Cells

    October 2020 in “ International Journal of Molecular Sciences ”
    Soyoon Park, Taesun Park, Dabin Choi, Bomin Son
    Studysummary This laboratory study found that nonanal, a plant scent compound, may stimulate growth factors and cell proliferation in human hair follicle dermal papilla cells, suggesting a cAMP-mediated mechanism.
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    Research cited in this study 20

    1. Shikimic Acid, a Mannose Bioisostere, Promotes Hair Growth with the Induction of Anagen Hair Cycle. Scientific Reports · 2019
    2. Olfactory Receptor OR2AT4 Regulates Human Hair Growth Nature Communications · 2018
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    7. Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia Journal of Investigative Dermatology · 2015
    8. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014
    9. Modulating Hair Follicle Size with Wnt10b/DKK1 During Hair Regeneration Experimental Dermatology · 2014
    10. Promotion Effect of Constituents from the Root of Polygonum Multiflorum on Hair Growth Bioorganic & Medicinal Chemistry Letters · 2013
    11. Maintenance of High Proliferation and Multipotent Potential of Human Hair Follicle-Derived Mesenchymal Stem Cells by Growth Factors International Journal of Molecular Medicine · 2013
    12. Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration Journal of Investigative Dermatology · 2012
    13. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010
    14. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004
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    1. Nonanal Stimulates Growth Factors via Cyclic Adenosine Monophosphate (cAMP) Signaling in Human Hair Follicle Dermal Papilla Cells International Journal of Molecular Sciences · 2020