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In this study, finasteride was found to enhance stem cell properties in dermal papilla cells, suggesting potential benefits for hair loss management and regenerative therapies.

This study found that circRNA-0100 promotes differentiation of secondary hair follicle stem cells into hair lineage in cashmere goats by sequestering miR-153-3p, which enhances KLF5 expression.

This study found that stem cells derived from root apical papilla in extracted wisdom teeth demonstrated the strongest potential for osteogenic differentiation compared to those from dental pulp and dental follicle.

This abstract explains that androgenetic alopecia, a common hair loss disorder influenced by genetics and hormones like dihydrotestosterone, has FDA-approved treatments including minoxidil, finasteride, and photolaser therapy, but its genetic basis and susceptibility to environmental factors remain complex.

This study found that silk fibroin/sodium alginate scaffolds seeded with dermal papilla cells may accelerate skin repair and hair follicle regeneration in a rat model.

This study provides scientific backing for the use of ECOHAIR® spray in patients with noncicatricial alopecia, showing improvements in hair volume, appearance, growth, and reduced hair loss over a 3-month period, with no local adverse effects reported.

This study suggests that policosanol may prevent androgenetic alopecia in mice by regulating hormone levels and suppressing premature hair follicle entry into the regression phase.

The study suggests hormonal factors may play a role in Frontal Fibrosing Alopecia and that treatments like oral antiandrogens and steroids could be beneficial.

In this study, researchers observed that the combination of hair progenitors and their micro-niche changes every three days in mouse zigzag hair, and disruptions in specific genes affected this rhythm, highlighting the importance of this periodic change for normal hair morphology.

This study suggests that human dermal fibroblasts can be converted into dermal papilla cell-like cells using microencapsulation, which may facilitate hair follicle regeneration in mice without chemical or genetic reprogramming.

This study developed a humanized scalp model in mice which demonstrated that transplanted cultured human hair follicle dermal cells contributed to the restoration of damaged hair follicles.

This article reviews the use of mesenchymal stem cells and biomimetic scaffolds in regenerative medicine, highlighting promising in vitro and in vivo outcomes, but it reports no new clinical results.

This study found that calcium microcapsules exhibited better biocompatibility and cell viability than barium microcapsules for scaffolding in artificial dermal papilla, suggesting potential for developing new hair follicle structures.

This study found that CARI ONE, a herbal mixture, promotes hair growth in mice by inducing the transition from telogen to anagen phase and enhancing hair follicle development, compared to control and minoxidil treatments.

This study suggests that Lindera strychnifolia root extract may help restore a healthy microbial balance on the scalp in men with androgenetic alopecia after 83 days of treatment.

This study investigated the use of 3D cell culture technology to explore hair follicle regeneration, examining the impact of the 3D cellular environment on hair follicle morphogenesis and the effects of microwell depth on spheroid formation.

In this study, male participants with early androgenetic alopecia experienced a significant increase in hair growth rate after applying topical lipoid cepharanthine lotion for six months.

This review outlines the transition from simple hair follicle organoids to immune-competent microphysiological systems, addressing limitations in replicating native hair follicle immune features and discussing their applications in disease modeling and regenerative medicine.

This study concluded that the CXCL12–CXCR4 signaling pathway significantly contributes to hair loss in androgenetic alopecia and alopecia areata by promoting inflammation and fibrosis, whereas inhibiting this pathway can restore hair growth and follicle health.

This study identified important lncRNAs and genes associated with cashmere shedding in goats and explored their regulatory interactions, providing insights into the molecular mechanisms that may underlie this phenomenon.

This source reviews recent data on topical minoxidil, evaluating its pharmacology, mechanism of action, clinical effectiveness, and side effects in treating hair loss, although its precise mode of action remains unclear.

This study observed that among male patients who experienced telogen effluvium after platelet-rich plasma treatment for androgenic alopecia, there were elevated levels of TNF-α, androgen receptors, and altered 5α-reductase gene expression, suggesting these factors as potential contributors to this unintended outcome.

This study found that intrinsic feedback loops are crucial for maintaining the function of human dermal papilla cells during hair growth, highlighting the importance of autocrine signaling and niche reprogramming for advancing hair follicle biology and regenerative therapies for hair loss.

This study found that inhibiting prolactin secretion during the telogen phase can reduce the number of activated secondary hair follicles and the width of hair bulbs.

This study identified a network of interactions between miRNAs and mRNAs that involve key signaling pathways, suggesting new insights into the mechanisms behind androgenetic alopecia.

This study suggests that phloroglucinol may enhance anagen signaling and reduce oxidative stress-induced damage in human dermal papilla cells, offering a potential therapy for hair loss.

This study found that Glehnia littoralis and Andrographis paniculata may support hair growth by protecting against oxidative stress and increasing VEGF and Wnt/β-catenin signaling in human hair follicle dermal papilla cells, with enhanced effects when combined.

This review highlights the potential of plant-derived molecules like Epigallocatechin-3-Gallate and Ginsenosides to promote healthy hair growth by enhancing nutrient supply and blood flow to the scalp, and notes their growing role in natural hair care product development.

This study found that nanovesicles derived from ReNcell VM cells promoted hair growth in mice by activating the Wnt/β-catenin signaling pathway, suggesting they may serve as an alternative to extracellular vesicles for hair growth therapy.

This paper reviews the role of miRNAs in stem cell therapies and hair follicle growth, reporting no new findings but highlighting recent insights into fertility treatment and wound healing.