research The Cellular Basis of Mechanosensory Merkel-Cell Innervation During Development
BMP signaling is essential for the development of touch domes.
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510-540 / 545 resultsresearch Opposing Impacts on Healthspan and Longevity by Limiting Dietary Selenium in Telomere Dysfunctional Mice
Low selenium levels can extend lifespan but worsen health issues.
research Potassium Channel Openers Increase Aortic Elastic Fiber Formation and Reverse the Genetically Determined Elastin Deficit in the Brown Norway Rat
Potassium channel openers help form elastic fibers in arteries and can treat elastin deficiency and hypertension.
research Minoxidil May Suppress Androgen Receptor-Related Functions
Minoxidil can reduce functions related to androgen receptors.
research Activating Beta-Catenin Signaling in CD133-Positive Dermal Papilla Cells Increases Hair Inductivity
Boosting β-catenin signaling in certain skin cells can enhance hair growth.
research Activation of Androgen Receptor Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
Breast cancer treatments work better with AR activation, improving results and reducing side effects.
research Endocrine Profile of the VCD-Induced Perimenopausal Model Rat
The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.
research The Importance of Basonuclin 2 in Adult Mice and Its Relation to Basonuclin 1
Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.
research An Epistatic Effect of KRT25 on SP6 Is Involved in Curly Coat in Horses
The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.
research Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes
A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.
research Dietary Vitamin A Impacts Refractory Telogen
Eating too much or too little vitamin A can cause hair loss.
research Minoxidil Nanoparticles Targeting Hair Follicles Enhance Hair Growth in C57BL/6 Mice
Minoxidil nanoparticles significantly boost hair growth in mice compared to regular minoxidil.
research How to Read a Research Paper: A Critical Examination of Tamsulosin and Dementia Risk
Tamsulosin may slightly increase dementia risk compared to other treatments for enlarged prostate.
research Anti-Wrinkle Effect of Bone Morphogenetic Protein Receptor 1a Extracellular Domain (BMPR1a-ECD)
BMPR1a-ECD reduces wrinkles much more effectively than retinoic acid.
research MG53 Mitigates Nitrogen Mustard-Induced Skin Injury
MG53 helps reduce skin damage caused by nitrogen mustard.
research The Clinical Management of Testosterone Replacement Therapy in Postmenopausal Women with Hypoactive Sexual Desire Disorder: A Review
Testosterone Replacement Therapy can improve sexual health in postmenopausal women with low sexual desire, but more research is needed on its long-term effects.
research Generating Induced Pluripotent Stem Cells with a High-Efficiency, Non-Invasive Method: An Improved Way to Cultivate Keratinocytes from Plucked Hair for Reprogramming
The conclusion is that the new method makes collecting cells from plucked hair to create stem cells more efficient and less invasive.
research Expression of Potential Dermal Progenitor Cell Markers in the Tumor and Stroma of Skin Adnexal Malignant and Benign Tumors
Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.
research Oral Presentations: Abstracts of the Urological Society of Australia and New Zealand Annual Scientific Meeting, Melbourne, Australia
Urologists should monitor mental health in patients taking finasteride due to potential links to suicidal thoughts, adjusting dosage or stopping use if necessary. More research is needed to confirm if finasteride causes these thoughts.
research Genomic and Transcriptomic Characterization of Atypical Recurrent Flank Alopecia in the Cesky Fousek
The study found that the hair loss condition in Cesky Fousek dogs is influenced by multiple genes affecting skin and muscle structure, fat metabolism, and immunity.
research De Novo Filament Formation by Human Hair Keratins K85 and K35 Follows a Filament Development Pattern Distinct from Cytokeratin Filament Networks
Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.
research Optimal Stimulation Toward the Dermal Papilla Lineage Can Be Promoted by Combined Use of Osteogenic and Adipogenic Inducers
Combining specific inducers helps dermal papilla cells regain hair-forming ability.
research Somatotropin Penetration Testing From Topical Formulations Applied to the Skin
The new topical growth hormone formula has high skin penetration and bioavailability.
research Isolation, Cultivation, and Morphological Characteristics of Hair Follicle Adult Stem Cells in the Bulge Region in Mouse and Human
Researchers successfully grew hair follicle stem cells from mice and humans, which could be useful for tissue engineering and regenerative medicine.
research Safety of Antiandrogens for the Treatment of Female Androgenetic Alopecia with Respect to Gynecologic Malignancies
Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.
research Pharmacotherapy for Keloids and Hypertrophic Scars
Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.
research The Role of Fractional Laser-Assisted Drug Delivery in Enhancing the Efficacy of Topical Bimatoprost Solution in the Treatment of Alopecia Areata: An Intra-Patient Comparative Randomized Clinical Trial
Using a laser with bimatoprost solution works better for hair regrowth in alopecia areata than bimatoprost alone.
research Serum Lipidomic Changes and Sex Differences in Androgenetic Alopecia
People with androgenetic alopecia have different lipid levels in their blood, which vary between men and women, and may be linked to a higher risk of metabolic syndrome.
research MSC-Derived Exosomes Protect Auditory Hair Cells From Neomycin-Induced Damage Via Autophagy Regulation
Tiny particles from stem cells can help protect ear cells from antibiotic damage by helping cells remove damaged parts.
research Follicle-Targeted Delivery of Betamethasone and Minoxidil Co-Entrapped in Polymeric and Lipid Nanoparticles for Topical Alopecia Areata Treatment
Tiny particles improved delivery of hair loss treatments to hair follicles, with lipid-based particles performing best.