Anti-Wrinkle Effect of Bone Morphogenetic Protein Receptor 1a Extracellular Domain (BMPR1a-ECD)
September 2013
in “
BMB Reports
”
TLDR BMPR1a-ECD reduces wrinkles much more effectively than retinoic acid.
The study investigated the anti-wrinkle effects of BMPR1a-ECD in a mouse model, finding that it significantly reduced wrinkle formation by inhibiting MMP expression and increasing collagen synthesis. BMPR1a-ECD showed a 6-fold stronger anti-wrinkle effect than retinoic acid and prevented UVB-induced epidermal thickening and procollagen loss. The results suggested that BMPR1a-ECD could be a promising therapeutic agent for treating skin wrinkles and potentially other skin or hair diseases, with further studies recommended to explore its mechanisms and applications.
