Activation of Androgen Receptor Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation

    December 2013 in “ Molecular cancer therapeutics ”
    Yu Wang, Qi Yu, Xin He … Charis Eng
    Studysummary This study found that AR-positive breast cancer cell lines are more sensitive to the dual PI3K/mTOR inhibitor NVP-BEZ235 compared to AR-negative cells.
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    1. Effects of Immunosuppressive Peptidyl-Prolyl Cis-Trans Isomerase (PPIase) Inhibitors, Cyclosporin A, FK506, Ascomycin, and Rapamycin, on Hair Growth Initiation in Mice: Immunosuppression Is Not Required for New Hair Growth Journal of Dermatological Science · 1995