February 2026 in “The Animal Biology” In this animal study, Hirudo verbana leech extract significantly improved hair follicle regeneration and accelerated wound healing in rats, demonstrating potential as a safe and effective agent for skin repair due to its bioactive compounds with regenerative and anti-inflammatory properties.
27 citations
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May 2017 in “Marine Drugs” This study found that Undariopsis peterseniana extract may promote hair growth by activating specific cellular pathways, suggesting potential for treating alopecia.
This study found that the Padina arborescens extract and its component MOGG may prevent hair loss by inhibiting 5α-reductase activity, promoting cell proliferation, opening the KATP channel, and increasing PGE2 production in laboratory settings.
July 2026 in “Physiologia Plantarum” In this study, researchers identified the crucial role of collet hairs in seedling survival by demonstrating that the collet hair-defective shv3 mutant lacked sufficient anchorage, compromising radicle penetration into the soil.
December 2024 in “Frontiers in Pharmacology” In this study, human cell models of hair follicles showed that araliadiol, a plant-derived polyacetylene compound, promotes hair growth through the p38/PPAR-γ signaling pathway, suggesting its potential as a new drug candidate for alopecia treatment.
September 2023 in “Mağallaẗ baġdād li-l-ʿulūm” This study found diverse and distinct microbial communities in dry and wet habitats of Duku plants, with varying relative abundances linked to plant health and soil nutrient interactions.
January 2026 in “Journal of Ethnopharmacology” Cedrol promotes hair growth better than baricitinib by regulating immune cells.
December 2024 in “Planta Medica” This systematic scoping review synthesized evidence from 175 in vivo studies on the effects of plant-based substances on hair growth, using animal models such as mice and rabbits. The authors created a checklist to improve data comparison and reproducibility in future hair growth research.
5 citations
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January 2010 in “Medicinal Plants - International Journal of Phytomedicines and Related Industries” This review discusses the diverse pharmacological activities of T. procumbens, such as hypotensive and hair growth-promoting effects, but reports no new clinical findings.
January 2025 in “International Journal of Endocrinology” This study found that the hydroalcoholic extract of the Dorema aucheri plant, especially at a 5% concentration, enhanced diabetic wound healing in male rats, improving re-epithelialization, collagen deposition, and neovascularization more effectively than other tested concentrations.
July 2023 in “Veterinary pathology” In this report, the researchers described a follicular dysplastic syndrome in two adult white-tailed deer, where gross alopecia and histologic signs suggestive of alopecia areata were observed, potentially predisposing affected deer to environmental exposure.
January 2017 in “한국약용작물학회지” This study suggests that 70% ethanol extracts from certain medicinal plants may promote hair growth and be useful for developing hair care products.
3 citations
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July 2018 in “DergiPark (Istanbul University)” This article reviews the usage of medicinal plants for treating certain conditions in European Turkey, detailing the plants' parts, preparatory methods, and traditional therapeutic applications but reports no new experimental results.
June 2023 in “Current Issues in Molecular Biology” In this study, the alcoholic extract DN106212 from Centipeda minima was shown to be more effective in promoting hair growth in C57BL/6 mice compared to dimethyl sulfoxide and tofacitinib, suggesting its potential as a natural hair growth agent.
In this study, the researchers used a human hair follicle model to demonstrate that T cell stimulation can induce an alopecia areata–like phenotype, with cell proliferation and immune privilege collapse; however, the DHODH inhibitor farudodstat partially mitigated these effects by reducing T cell proliferation.
December 2024 in “Plant Science Today” This study investigated the therapeutic potential of phytochemicals from Phyla nodiflora, identifying 50 bioactive compounds through GC-MS analysis. Among them, n-hexadecanoic acid, stigmasterol, and beta-sitosterol showed promise in molecular docking studies as drug candidates for diabetes, alopecia, cancer, and anti-diuresis.
1 citations
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October 2010 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” This review discusses the effectiveness of various plant extracts, including Vitis vinifera and Aesculus hippocastanum, in treating dermatological conditions like venous insufficiency and actinic keratoses but reports no new clinical results.
1 citations
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June 2023 in “International journal of basic science in medicine” In this review, the potential medicinal benefits of Adiantum capillus-veneris L. (a plant used in traditional medicine) were highlighted, particularly its antioxidant, antimicrobial, and anti-inflammatory effects, although the authors noted the need for more research on its impact on respiratory diseases.
6 citations
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December 2019 in “BMC Complementary and Alternative Medicine” This study found that the alcohol extract of Vernonia anthelmintica may counteract stress-induced hair follicle growth inhibition in mice, potentially offering a new approach for treating stress-related hair loss.
3 citations
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November 2020 in “Phyton-international Journal of Experimental Botany” This review discusses the potential therapeutic applications of wedelolactone, a compound in Eclipta prostrata, for various chronic human diseases and reports no new clinical results.
13 citations
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January 2014 in “Zhongguo zhongyao zazhi” This study found that Dendrobium candidum polysaccharides might promote hair growth in mice, potentially by increasing VEGF mRNA expression.
April 2018 in “Journal of Investigative Dermatology” This study found that terminally differentiated effector memory Vδ1T-cells and their cytotoxic activation markers were elevated in alopecia areata patients, suggesting these cells may contribute to its early pathogenesis.
5 citations
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March 2023 in “Journal of Cosmetic Dermatology” This study reports that Plantago asiatica L. extract may promote hair growth by enhancing growth factor production and activating specific signaling pathways in hair follicle dermal papilla cells.
This study found that ingesting seeds from the Lecythis ollaria tree may cause hair loss and other toxic effects in animals.
October 2025 in “Quantum Journal of Medical and Health Sciences” This review outlines the phytochemical composition and pharmacological potential of Tridax procumbens, a plant traditionally used in various regions for its purported medical benefits, including antioxidant, antimicrobial, and anti-inflammatory effects, among others.
14 citations
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July 2016 in “Environmental Toxicology and Pharmacology” In this animal study, cedrol treatment reduced chemotherapy-induced alopecia in mice by preventing hair follicle damage, while minoxidil did not prevent alopecia under similar conditions.
15 citations
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July 2004 in “Journal of Wildlife Diseases” In this study, ivermectin treatment in affected Columbian black-tailed deer was associated with increased weight gain, reduced parasites, and faster hair regrowth compared to untreated deer.
1 citations
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June 2023 in “International Journal of Pharmaceutical Sciences and Medicine” This review found that Sansevieria trifasciata contains numerous chemical compounds and has been traditionally used to treat various ailments, with prior studies confirming its pharmacological activities such as anti-ulcer, antibacterial, antioxidant, antidiabetic, and anticancer effects, among others.
January 2025 in “International Journal of Advanced Research in Science Communication and Technology” This review summarizes the pharmacological and therapeutic uses of Calotropis gigantea latex, noting its traditional applications in treating skin diseases, wounds, and asthma, as well as its potential in addressing cancer, diabetes, and cardiovascular diseases due to its rich bioactive compound content.
11 citations
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May 1990 in “Journal of Dermatological Science” In this animal study, topical diazoxide treatment led to increased hair thickness and follicle growth in bald stumptailed macaques without causing notable systemic side effects.