Orchestrated Cytotoxic and Skin Migratory Ability Lacking Self-Tolerance: Circulating γδT-Cells May Promote Alopecia Areata

April 2018 in “ Journal of Investigative Dermatology ”

Youhei Uchida, Takurou Kanekura

alopecia areata γδT-cells cytotoxic skin migratory ability self-tolerance AA

TLDR The role of γδT-cells in causing alopecia areata remains unclear.

The study investigated the role of circulating γδT-cells in alopecia areata (AA), involving 6 patients with AA and 3 healthy donors. The study aimed to understand the cytotoxic and skin migratory abilities of these cells and their potential to promote AA due to a lack of self-tolerance. However, the document does not provide any conclusions or significant findings from the study, leaving the role of γδT-cells in AA unclear.

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