Experimental Study on Dendrobium Candidum Polysaccharides on Promotion of Hair Growth

    January 2014 in “ Zhongguo zhongyao zazhi
    Chen Jian, Hui Qi, Jin-Biao Li, Yan-Qun Yi, Dan Chen, Xianwei Hu, Meiling Wang, Xing-li Sun, Xiaoyong Wei
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    Studysummary This study found that Dendrobium candidum polysaccharides might promote hair growth in mice, potentially by increasing VEGF mRNA expression.
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    The study investigated the effects of Dendrobium candidum polysaccharides (DCP) on hair growth using 30 C57BL/6J mice. The mice were divided into three groups: control, positive control (minoxidil), and DCP. Over 21 days, hair growth was evaluated, and results showed that the DCP group had significantly higher hair growth scores and hair weight compared to the control group. Additionally, DCP increased the survival rate and mRNA expression of VEGF in HaCaT cells, suggesting that DCP promotes hair growth potentially through up-regulation of VEGF mRNA expression.
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