TLDR Wedelolactone may help treat chronic diseases by acting as an antioxidant and affecting important proteins.
The review from 2021 investigated the biological and functional properties of Wedelolactone (WDL), a bioactive compound in Eclipta prostrata L, and its potential benefits against chronic human diseases. The study compiled information from various scientific databases such as PubMed, Web of Science, Science Direct, and Google Scholar. The diseases studied included cardiovascular disease, cancer, diabetes mellitus, liver disease, Alzheimer’s disease, and androgenetic alopecia. The review concluded that WDL acts as a key antioxidant and both a regulator and inhibitor of major drug targetable proteins in chronic human diseases. The authors suggested further exploration of WDL as a potential therapeutic bioactive molecule for its pharmacological activities.
Cited in this study
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46 citations
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December 2019 in “Journal of Ethnopharmacology” Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.
7 citations
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January 2019 in “Pharmaceutical Biology” Eclipta prostrata helps hair growth and maintains the growth phase by affecting certain growth factors.
99 citations
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July 2017 in “Clinical Reviews in Allergy & Immunology” New treatments for Alopecia Areata show promise but need to be more effective and affordable.
178 citations
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July 2017 in “Journal of The American Academy of Dermatology” Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.
101 citations
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January 2016 in “Journal of Cutaneous and Aesthetic Surgery” Different types of hair loss need specific treatments, and while many classification systems exist, each has its flaws; more research is needed to refine these systems and treatments.
29 citations
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December 2014 in “Current Opinion in Endocrinology, Diabetes and Obesity” Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.
98 citations
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May 2008 in “Archives of Dermatological Research” Eclipta alba extract helps hair grow faster and more effectively than minoxidil in rats.