Biological and Functional Properties of Wedelolactone in Human Chronic Diseases

November 2020 in “ Phyton-international Journal of Experimental Botany ”

Ramachandran Vinyagam, Pradeep Kumar, Jun Young Lee, XU Bao-jun, Muhammad Nurul Matin, Sang Gu Kang

Wedelolactone Eclipta prostrata androgenetic alopecia antioxidant WDL false daisy

TLDR Wedelolactone may help treat chronic diseases by acting as an antioxidant and affecting important proteins.

The review from 2021 investigated the biological and functional properties of Wedelolactone (WDL), a bioactive compound in Eclipta prostrata L, and its potential benefits against chronic human diseases. The study compiled information from various scientific databases such as PubMed, Web of Science, Science Direct, and Google Scholar. The diseases studied included cardiovascular disease, cancer, diabetes mellitus, liver disease, Alzheimer’s disease, and androgenetic alopecia. The review concluded that WDL acts as a key antioxidant and both a regulator and inhibitor of major drug targetable proteins in chronic human diseases. The authors suggested further exploration of WDL as a potential therapeutic bioactive molecule for its pharmacological activities.

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