Cedrol From Platycladus Orientalis Regulates M1/M2 Polarization of Macrophages and Promotes Hair Regeneration

    January 2026 in “ Journal of Ethnopharmacology ”
    Tao Li, Lizhen Lin, Xinyang Zhou … Yuqing Zhao
    Studysummary Cedrol promotes hair growth better than baricitinib by regulating immune cells.
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    Research cited in this study 13

    1. Platycladus Orientalis Leaf Extract Promotes Hair Growth Via Non-Receptor Tyrosine Kinase ACK1 Activation Current Issues in Molecular Biology · 2024
    2. Cedrol in Ginger (Zingiber Officinale) as a Promising Hair Growth Drug: The Effects of Oral and External Administration on Hair Regeneration and Its Mechanism Bioorganic Chemistry · 2024
    3. Amygdalin Ameliorates Alopecia Areata on C3H/HeJ Mice by Inhibiting Inflammation Through JAK2/STAT3 Pathway Journal of Ethnopharmacology · 2024
    4. Alopecia Areata: Current Treatments and New Directions American Journal of Clinical Dermatology · 2023
    5. Alopecia Areata: Case Report and Review of Pathophysiology and Treatment with JAK Inhibitors Journal of autoimmunity · 2022
    6. Hair Follicle-Derived Mesenchymal Stem Cells Decrease Alopecia Areata Mouse Hair Loss and Reduce Inflammation Around the Hair Follicle Stem Cell Research & Therapy · 2021
    7. Topical Tofacitinib for the Treatment of Alopecia Areata Affecting Facial Hair British Journal of Dermatology · 2021
    8. In Vivo and In Vitro Evaluation of Hair Growth Potential of Cacumen Platycladi, and GC-MS Analysis of the Active Constituents of Volatile Oil Journal of ethnopharmacology · 2019
    9. Hair Growth Promotion Effect of Cedrol Cream and Its Dermatopharmacokinetics RSC Advances · 2018
    10. Alopecia Areata: What’s New in Epidemiology, Pathogenesis, Diagnosis, and Therapeutic Options? Journal of dermatological science · 2016
    11. Preventive Effects of Cedrol Against Alopecia in Cyclophosphamide-Treated Mice Environmental Toxicology and Pharmacology · 2016
    12. Hair Growth Promoting Activity of Cedrol Isolated from the Leaves of Platycladus Orientalis Biomedicine & Pharmacotherapy · 2016
    13. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010