Search
for

    Glossary DNase-seq

    identifies accessible DNA regions by sequencing DNase I cut sites

    DNase-seq, also known as DNase I hypersensitive sites sequencing, is a technique used to identify regions of the genome that are accessible and likely to be involved in gene regulation. By treating DNA with the enzyme DNase I, which cuts DNA at these accessible sites, researchers can sequence the resulting fragments to map areas where regulatory proteins, such as transcription factors, are likely to bind. This method helps in understanding how genes are turned on or off in different cell types and conditions.

    Sort by

    Research 30 of 793

    1. Identification and dissection of an enhancer controlling epithelial gene expression in skin Proceedings of the National Academy of Sciences · 2001 · 29 citations
    2. Defining the identity of mouse embryonic dermal fibroblasts Genesis · 2016 · 21 citations
    3. Basonuclin is associated with the ribosomal RNA genes on human keratinocyte mitotic chromosomes Journal of Cell Science · 1999 · 36 citations
    4. Transcriptome sequencing and identification of cytochrome P450 monooxygenases involved in the biosynthesis of maslinic acid and corosolic acid in <i>Avicennia marina</i> Plant Biotechnology · 2018 · 10 citations
    5. Alopecia areata susceptibility variant identified by MHC risk haplotype sequencing reproduces symptomatic patched hair loss in mice bioRxiv (Cold Spring Harbor Laboratory) · 2018
    6. Transcriptome Sequencing Reveals Differences between Primary and Secondary Hair Follicle-derived Dermal Papilla Cells of the Cashmere Goat (Capra hircus) PLoS ONE · 2013 · 81 citations
    7. Comparative study on seasonal hair follicle cycling by analysis of the transcriptomes from cashmere and milk goats Genomics · 2019 · 25 citations
    8. Wound healing mechanism in Mongolian gerbil skin Histochemistry and Cell Biology · 2018 · 6 citations
    9. Regulatory network of ginsenoside biosynthesis under Ro stress in the hairy roots of Panax ginseng revealed by RNA sequencing Frontiers in bioengineering and biotechnology · 2022 · 5 citations
    10. Investigation of Transcriptional Gene Profiling in Normal Murine Hair Follicular Substructures Using Next-Generation Sequencing to Provide Potential Insights into Skin Disease Cell Transplantation · 2016 · 1 citations
    11. In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators Nature Cell Biology · 2014 · 173 citations
    12. Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing Science Advances · 2021 · 66 citations
    13. Single-Cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Related Potentially to the Fineness of Cashmere Fiber Frontiers in Genetics · 2021 · 3 citations
    14. Wasabi leaf extract changes the expression levels of cytokine related genes in dermal papilla cells, which identified by the whole transcriptome 2025
    15. The role of the skin microbiome in wound healing Burns and trauma · 2023
    16. De novo single-nucleotide and copy number variation in discordant monozygotic twins reveals disease-related genes European Journal of Human Genetics · 2019 · 36 citations
    17. Genome-wide detection and sequence conservation analysis of long non-coding RNA during hair follicle cycle of yak BMC Genomics · 2020 · 13 citations
    18. Evolving approaches to profiling the microbiome in skin disease Frontiers in immunology · 2023 · 9 citations
    19. Integrated analysis of lncRNAs and mRNAs by RNA-Seq in secondary hair follicle development and cycling (anagen, catagen and telogen) of Jiangnan cashmere goat (Capra hircus) BMC Veterinary Research · 2022 · 24 citations
    20. Chemotherapy-induced toxicity—a secondary effect caused by released DNA? Annals of Oncology · 2017 · 13 citations
    21. SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder Cell · 2010 · 260 citations
    22. An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin Developmental cell · 2015 · 173 citations
    23. Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes Nucleic Acids Research · 2002 · 79 citations
    24. Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration Cell Reports · 2023 · 44 citations
    25. Sustained Exosome‐Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and MiRNAs, and Sustained Release Formulation Small · 2022 · 40 citations
    26. Transcriptome-based selection and validation of optimal house-keeping genes for skin research in goats (Capra hircus) BMC Genomics · 2020 · 23 citations
    27. Study of seed hair growth in Populus tomentosa, an important character of female floral bud development BMC genomics · 2014 · 20 citations
    28. <i>De Novo</i>Transcriptome Assembly and Differential Gene Expression Profiling of Three<i>Capra hircus</i>Skin Types during Anagen of the Hair Growth Cycle International Journal of Genomics · 2013 · 12 citations
    29. Single‐cell transcriptomics reveals a senescence‐associated IL ‐6/ CCR6 axis driving radiodermatitis EMBO molecular medicine · 2022 · 9 citations
    30. The Enrichment of Specific Hair Follicle-Associated Cell Populations in Plucked Hairs Offers an Opportunity to Study Gene Expression Underlying Hair Traits International journal of molecular sciences · 2022 · 2 citations