Evolving Approaches to Profiling the Microbiome in Skin Disease

    April 2023 in “ Frontiers in immunology
    Yang Chen, Rob Knight, Richard L. Gallo
    Image of study
    TLDR New technologies help us better understand how skin microbes affect skin diseases.
    Human skin hosts diverse microbes that interact with the immune system and can influence conditions like atopic dermatitis, acne, and psoriasis. Dysbiosis, or imbalances in these microbial communities, is linked to these disorders. Traditional 16S rRNA gene sequencing methods are limited, but new technologies like metagenomics offer more detailed insights. Understanding the complex dynamics of the skin microbiome, including inter-species interactions and their systemic effects, requires advanced profiling methods and clinical trials. This review highlights current and emerging techniques to better understand the microbiome's role in skin health and disease.
    Discuss this study in the Community →

    Research cited in this study

    5 / 5 results

    Related Community Posts Join

    6 / 39 results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 8 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  413 upvotes 2 weeks ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community How uninformed the general public is about hair loss

      in Chat  314 upvotes 1 year ago
      The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

    Similar Research

    5 / 1000+ results