TLDR Acne is linked to complex skin microbe interactions, and new findings suggest microbiome-based treatments could be effective.
The document discussed the interactions between the host and microbiome in the context of acne vulgaris, focusing on the role of Propionibacterium acnes (P. acnes) and its biofilms in acne development. It highlighted the genetic diversity and pathogenic potential of P. acnes, its ability to trigger inflammatory responses, and the importance of the skin microbiome's balance. Recent advancements included the potential of nitric oxide-releasing nanoparticles, probiotics, dietary interventions, photothermolysis using gold microparticles, and vaccines targeting P. acnes as promising therapeutic strategies to reduce inflammation and acne severity.
59 citations,
October 2016 in “Clinics in dermatology” Precise skin sampling is crucial to understand the role of P. acnes in acne.
138 citations,
July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
35 citations,
March 2012 in “Journal of dermatological science” The document concludes that advanced methods show the presence of P. acnes in acne lesions but do not prove it causes acne.
49 citations,
September 2008 in “International journal of pharmaceutics” Artificial sebum L closely mimics human sebum for drug delivery research.
9 citations,
April 2023 in “Frontiers in immunology” New technologies help us better understand how skin microbes affect skin diseases.
73 citations,
April 2019 in “Experimental Dermatology” The scalp's microorganisms significantly affect hair health and disease.
April 2024 in “Frontiers in cellular and infection microbiology” Blue light might help treat skin conditions by affecting the skin's bacteria.
4 citations,
March 2022 in “BioEssays” Hydra can help understand human hair follicle microbiomes and develop new skin disease therapies.
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” Research on the human skin microbiome has grown, focusing on skin health and diseases, with more studies needed on antibiotic resistance and AI applications.
