TLDR Precise skin sampling is crucial to understand the role of P. acnes in acne.
The document reviewed the role of Propionibacterium acnes (P. acnes) in acne vulgaris, highlighting the importance of skin sampling methodologies. Despite extensive research, the exact role of P. acnes in acne remained unclear. Studies showed no significant difference in P. acnes counts between acne patients and healthy individuals, and inflammation was observed in lesions without bacterial presence. The review emphasized the need for precise sampling and detection techniques to better understand the bacterium's involvement in acne.
35 citations,
March 2012 in “Journal of dermatological science” The document concludes that advanced methods show the presence of P. acnes in acne lesions but do not prove it causes acne.
103 citations,
September 2004 in “Clinics in dermatology” Blocked hair follicles cause acne, and studying tiny early acne spots helps understand its severity.
405 citations,
January 2004 in “Journal of Investigative Dermatology” Hair follicle size and distribution vary significantly across different body sites.
194 citations,
October 2018 in “Microbiome” Acne is linked to complex skin microbe interactions, and new findings suggest microbiome-based treatments could be effective.
47 citations,
March 2022 in “Frontiers in cellular and infection microbiology” Changes in skin microbes play a role in some skin diseases and could lead to new treatments.
9 citations,
April 2023 in “Frontiers in immunology” New technologies help us better understand how skin microbes affect skin diseases.
11 citations,
February 2021 in “Biomedicines” Bacteria in our hair can affect its health and growth, and studying these bacteria could help us understand hair diseases better.
13 citations,
October 2012 in “InTech eBooks” Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
