Understanding the Role of Propionibacterium Acnes in Acne Vulgaris: The Critical Importance of Skin Sampling Methodologies

October 2016 in “ Clinics in dermatology ”

Hélène Omer, Andrew McDowell, Oleg A. Alexeyev

Propionibacterium acnes acne vulgaris skin sampling methodologies inflammation lesions P. acnes acne

TLDR Precise skin sampling is crucial to understand the role of P. acnes in acne.

The document reviewed the role of Propionibacterium acnes (P. acnes) in acne vulgaris, highlighting the importance of skin sampling methodologies. Despite extensive research, the exact role of P. acnes in acne remained unclear. Studies showed no significant difference in P. acnes counts between acne patients and healthy individuals, and inflammation was observed in lesions without bacterial presence. The review emphasized the need for precise sampling and detection techniques to better understand the bacterium's involvement in acne.

View this study on sciencedirect.com →

Discuss this study in the Community →

Research cited in this study

4 / 4 results

research Proteome Analysis of Human Sebaceous Follicle Infundibula Extracted from Healthy and Acne-Affected Skin

62 citations , September 2014 in “PLoS ONE”

Acne-affected skin has more inflammation-related proteins and bacteria than healthy skin.

research Pattern of Tissue Invasion by Propionibacterium Acnes in Acne Vulgaris

35 citations , March 2012 in “Journal of dermatological science”

The document concludes that advanced methods show the presence of P. acnes in acne lesions but do not prove it causes acne.

research Comedone Formation: Etiology, Clinical Presentation, and Treatment

103 citations , September 2004 in “Clinics in dermatology”

Blocked hair follicles cause acne, and studying tiny early acne spots helps understand its severity.

research Variations of Hair Follicle Size and Distribution in Different Body Sites

405 citations , January 2004 in “Journal of Investigative Dermatology”

Hair follicle size and distribution vary significantly across different body sites.

Related Community Posts Join

3 / 3 results

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 61 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 58 upvotes 1 year ago

Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

Similar Research

6 / 640 results

research Nanocarrier Systems for Transdermal Drug Delivery

13 citations , October 2012 in “InTech eBooks”

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

research The Human Skin Microbiome in Selected Cutaneous Diseases

47 citations , March 2022 in “Frontiers in cellular and infection microbiology”

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

research The Potential Relevance of the Microbiome to Hair Physiology and Regeneration: The Emerging Role of Metagenomics

11 citations , February 2021 in “Biomedicines”

Bacteria in our hair can affect its health and growth, and studying these bacteria could help us understand hair diseases better.

research Research and Development of Cosmetic Products for Men with Essential Oils: Skin Characterization, Clinical Efficacy, Consumer Profile, and Advertising Influence

April 2021

Men's skincare products with essential oils can improve skin health and may increase male interest in cosmetics.

research Host-Microbiome Interactions and Recent Progress in Understanding the Biology of Acne Vulgaris

194 citations , October 2018 in “Microbiome”

Acne is linked to complex skin microbe interactions, and new findings suggest microbiome-based treatments could be effective.

research Understanding the Impact of the Skin Microbiome on Dermatological Assessments and Therapeutic Innovation

November 2025 in “Dermato”

The skin microbiome is crucial for skin health and new treatments like probiotics can improve skin conditions.