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    Glossary ATAC-seq

    technique identifies open chromatin regions to study gene regulation

    ATAC-seq, or Assay for Transposase-Accessible Chromatin using sequencing, is a technique used to study the accessibility of chromatin, which is the material that makes up chromosomes. By identifying regions of DNA that are open and accessible, ATAC-seq helps researchers understand which parts of the genome are active and potentially involved in gene regulation. This method is valuable for studying gene expression patterns in various biological contexts, including development, disease, and cellular responses.

    Research 10 of 160

    1. 164 Epigenetic and transcriptional profiling of PBMCs in mild and severe alopecia areata using single-cell RNA-Seq and ATAC-Seq Journal of Investigative Dermatology · 2023
    2. 1378 A multi-omics approach to identifying factors involved in hair follicle growth and development Journal of Investigative Dermatology · 2023
    3. Deciphering a Message from the Nucleus: How Transcription Factors and Spatial Chromatin Interactions Orchestrate Epidermal Differentiation 2023
    4. Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease bioRxiv (Cold Spring Harbor Laboratory) · 2022
    5. States and Fates of Skin Fibroblasts Revealed through Chromatin Accessibility Journal of Investigative Dermatology · 2022
    6. 708 Promotion of hair growth in alopecia areata by topical treatment of HDAC inhibitors 2019
    7. 1418 Characterization of ectomesenchyme as an origin of epidermal stem cells Journal of Investigative Dermatology · 2023
    8. Single-cell chromatin landscapes of mouse skin development Scientific Data · 2022 · 2 citations
    9. Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing Cell stem cell · 2020 · 128 citations
    10. Single cell analysis of transcriptome and open chromatin reveals the dynamics of hair follicle stem cell aging Frontiers in Aging · 2023 · 3 citations
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