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GlossaryFAIRE-seq

technique to identify active regulatory regions in the genome

FAIRE-seq, or Formaldehyde-Assisted Isolation of Regulatory Elements sequencing, is a technique used to identify regions of the genome that are active in regulating gene expression. It works by using formaldehyde to crosslink DNA and proteins, then isolating the DNA that is not tightly bound to proteins, which typically corresponds to regulatory elements like enhancers and promoters. This isolated DNA is then sequenced to map these regulatory regions across the genome.

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research Identification and Molecular Characterization of a New Ovarian Cancer Susceptibility Locus at 17q21.31

106 citations , March 2013 in “Nature Communications”

A new genetic region, 17q21.31, is linked to higher ovarian cancer risk.

research Epigenetic Regulation and Factors That Influence the Effect of iPSCs-Derived Neural Stem/Progenitor Cells (NS/PCs) in the Treatment of Spinal Cord Injury

13 citations , February 2024 in “Clinical Epigenetics”

Epigenetic factors affect the success of using iPSC-derived cells for spinal cord injury treatment.

research Defining the Identity of Mouse Embryonic Dermal Fibroblasts

21 citations , June 2016 in “Genesis”

Researchers identified specific genes that are important for mouse skin cell development and healing.

research The Hairless Gene of the Mouse

4 citations , May 2006 in “médecine/sciences”

The hairless gene is crucial for hair health, and its mutations cause hair loss.

research The Pathophysiology of Polycystic Ovary Syndrome

249 citations , November 2003 in “Clinical endocrinology”

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

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community Average tressless user after taking oral minoxidil

in Satire 1441 upvotes 2 years ago

The conversation is about hair loss and the use of minoxidil (Minoxidil) and finasteride (Fin) as treatments. The conclusion is that some users have seen success in maintaining their hair with minoxidil, but there are varying opinions on the effectiveness of the treatments.

community I have a question for everyone about the new UCLA research

in Chat 11 upvotes 7 months ago

The conversation discusses skepticism about a new hair loss treatment called project K, which claims to replicate a chemical from UCLA research but is suspected to be a scam. The original poster plans to continue using oral minoxidil, finasteride, and dutasteride, along with microneedling, for hair regrowth.

community Can I punch someone if they make fun of my hair loss, just like Will Smith did?

in Chat 448 upvotes 3 years ago

Hair loss's social impact, focusing on Will Smith defending Jada Pinkett Smith's alopecia. The conversation highlights double standards between men and women experiencing hair loss and emphasizes empathy.

community How likely do you think it is for PP405 to come out?

in Research/Science 21 upvotes 2 months ago

PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

community 2550 fue hair transplant & dutasteride 0.5mg new journey

in Transplants 47 upvotes 1 year ago

A user underwent a 2,550 FUE hair transplant and started taking dutasteride 0.5mg. They previously tried RU58841, minoxidil, and microneedling but avoided finasteride and dutasteride due to side effects.

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