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GlossaryDNase-seq

DNase-seq, also known as DNase I hypersensitive sites sequencing, is a technique used to identify regions of the genome that are accessible and likely to be involved in gene regulation. By treating DNA with the enzyme DNase I, which cuts DNA at these accessible sites, researchers can sequence the resulting fragments to map areas where regulatory proteins, such as transcription factors, are likely to bind. This method helps in understanding how genes are turned on or off in different cell types and conditions.

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research Defining the identity of mouse embryonic dermal fibroblasts

21 citations , June 2016 in “Genesis”

Researchers identified specific genes that are important for mouse skin cell development and healing.

research From bedside to bench: regulation of host factors in SARS-CoV-2 infection

4 citations , April 2021 in “Experimental and Molecular Medicine”

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

research Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

308 citations , December 2018 in “PLOS Genetics”

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

research IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes

32 citations , February 2020 in “The Journal of clinical investigation/The journal of clinical investigation”

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

Differential gene expression analysis between anagen and telogen of Capra hircus skin based on the de novo assembled transcriptome sequence

research Differential gene expression analysis between anagen and telogen of Capra hircus skin based on the de novo assembled transcriptome sequence

31 citations , May 2013 in “Gene”

Signaling pathways are crucial for hair growth in goats.

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community I hate how my hair loss changed me.

in Chat 169 upvotes 3 years ago

A man's experience with hair loss, which has caused him to lose an important part of his identity, and the treatments he is using to try and combat it. Others have joined in the conversation to share their own experiences and offer support.