research Rothmund-Thomson Syndrome Type 2 – A Rare Cause of Chronic Wounds
Rothmund-Thomson syndrome type 2 can cause chronic, poorly healing wounds.
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research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research Profiling the Response of Human Hair Follicles to Ultraviolet Radiation
UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.
research Recent Advances in Exosomal Non-Coding RNA-Based Therapeutic Approaches for Photoaging
New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.
research Cutaneous Reactions to Recombinant Cytokine Therapy
Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.
research In Silico Analysis of the Age-Dependent Evolution of the Transcriptome of Mouse Skin Stem Cells
The research found that the gene activity in mouse skin stem cells changes significantly as they age.
research The Role of Mitochondria in the Non-Targeted Effect of Ionizing Radiation
Mitochondria may influence how cells respond to radiation, affecting nearby non-irradiated cells.
research Geriatric Dermatology: Overview
Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.
research Molecular Mechanisms of Viral Oncogenesis in Humans
Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
research The Roles of Wnt/β-Catenin Pathway in Tissue Development and Regenerative Medicine
The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
research FOXO1, TGF-β Regulation and Wound Healing
FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.
research Cell Cycle Regulation and Regeneration
Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
research Skin Biology: Understanding Biological Targets for Improving Appearance
The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.
research Heavy Metals in Biological Samples of Cancer Patients: A Systematic Literature Review
Heavy metals like arsenic, cadmium, and lead can increase cancer risk and worsen outcomes.
research Milestones in Photocarcinogenesis
UV radiation causes skin cancer, but sunscreens and certain drugs can help prevent it.
research Do Changes in Chromosomes Cause Aging?
Chromosomal changes, including those in the WRN gene and rDNA, may significantly contribute to aging.
research Montagna Symposium 2013: Light and Skin - How Light Sustains, Damages, Treats, Images, and Modifies Skin Biology
Light affects skin health, aging, and cancer risk, and new light-based treatments and imaging are promising for skin care.
research Protective Role of Melatonin and Its Metabolites in Skin Aging
Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research CXXC5: A Novel Regulator and Coordinator of TGF-β, BMP, and Wnt Signaling
CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.
research Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes
Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.
research Contribution of Environmental Constituents in the Genomic Disruption of Cytokeratins
Environmental factors can cause mutations in skin proteins, leading to skin disorders.
research New Frontiers in CRISPR/Cas9 Delivery Systems for Gene Editing
Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.
research Equine Epidermis: A Source of Epithelial-Like Stem/Progenitor Cells with In Vitro and In Vivo Regenerative Capacities
Horse skin stem cells combined with platelet-rich plasma improve skin healing.
research Innate Immunity and the Regulation and Mobilization of Keratinocyte Stem Cells: Are the Old Players Playing a New Game?
Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.
research Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells
Allopregnanolone changes gene expression in glioblastoma cells.
research The Dark and the Bright Sides of the Transcription Factor Nrf2 in Skin Protection and Disease
Nrf2 helps protect skin from damage but too much can cause skin problems.
research Clinical Impact of Molecular Diagnostics in Endocrinology
Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.
research A Case of Relapsed Leprosy Successfully Treated With Sparfloxacin
A man's relapsed leprosy was successfully treated with the antibiotic sparfloxacin.
research British Cosmetic Dermatology Group Study on Imiquimod for Xeroderma Pigmentosum
Imiquimod improved skin pigmentation in most patients with xeroderma pigmentosum and may prevent further skin cancer, but some treatments can have side effects.