In Silico Analysis of the Age-Dependent Evolution of the Transcriptome of Mouse Skin Stem Cells

    January 2020 in “ Cells ”
    L. Francisco Lorenzo‐Martín, Xosé R. Bustelo
    Studysummary This study found that the transcriptome of skin stem cells in mice changes significantly with age, revealing specific age-dependent biological programs and transcriptional hubs.
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    Research cited in this study 7

    1. Gata6 Promotes Hair Follicle Progenitor Cell Renewal by Genome Maintenance During Proliferation The EMBO Journal · 2016
    2. Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition Cell stem cell · 2016
    3. Age-Associated Inflammation Inhibits Epidermal Stem Cell Function Genes & development · 2012
    4. The Circadian Molecular Clock Creates Epidermal Stem Cell Heterogeneity Nature · 2011
    5. Genome-Wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage Cell stem cell · 2011
    6. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    7. Nfatc1 Balances Quiescence and Proliferation of Skin Stem Cells Cell · 2008