59 citations,
August 2021 in “Frontiers in Endocrinology” GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
1 citations,
June 2023 in “Genes” Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.
August 2022 in “Gene Reports” New hair loss treatments could be improved by using combined biological markers.
45 citations,
April 2019 in “International Immunology” The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.
35 citations,
July 2008 in “Dermatologic therapy” Cicatricial alopecia may be caused by immune attacks on hair follicles, gland issues, or stem cell damage.
40 citations,
October 2012 in “Dermatologic clinics” More research is needed to understand the genetic causes of Alopecia areata to develop better treatments.
40 citations,
November 2019 in “Frontiers in Endocrinology” Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.
2 citations,
November 2020 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Redefining drug dosages is crucial when repurposing them for new uses.
October 2023 in “Psychiatry research. Case reports” A new HRAS gene variant may cause a range of symptoms including intellectual disability and psychiatric issues.
13 citations,
January 2023 in “Frontiers in Nutrition” Lindera aggregata has many beneficial compounds that can help prevent and manage diseases.
7 citations,
July 2019 in “International archives of internal medicine” Common skin conditions can greatly affect a person's mental health and social life.
1 citations,
February 2020 in “The Journal of clinical investigation/The journal of clinical investigation” Certain cancer drugs interact with skin bacteria to cause acne-like rashes.
November 2024 in “Frontiers in Medicine” Cirrhosis affects quality of life with various symptoms, requiring a holistic, multidisciplinary approach for management.
January 2024 in “Metabolites” Standardized procedures are crucial for collecting and preparing biological samples to ensure accurate clinical metabolomics results.
48 citations,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.
31 citations,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Different hair growth problems are caused by genetic issues or changes in hair growth cycles, and new treatments are being developed.
1113 citations,
August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
June 2006 in “British Journal of Dermatology” Lower adrenal hormone levels may cause hair loss in postmenopausal women, certain patterns help diagnose nail cancer, and a gene variant linked to higher skin cancer risk in kidney transplant patients suggests monitoring folate levels.
290 citations,
December 2017 in “Journal of The American Academy of Dermatology” Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.
37 citations,
March 1990 in “The Journal of Pediatrics” Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.
11 citations,
July 2012 in “Current Opinion in Pediatrics” Skin problems can be signs of hormone-related disorders and recognizing them early is important for treatment.
1 citations,
April 2017 in “Journal of Investigative Dermatology” Higher minoxidil dose helps hair growth in non-responders without side effects.
April 2017 in “Journal of Investigative Dermatology” Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.
77 citations,
June 2017 in “Advances in Therapy” New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.
33 citations,
September 2017 in “Journal of clinical immunology” New treatments for immune disorders caused by FOXN1 deficiency are promising.
3 citations,
May 2018 in “InTech eBooks” Animal models, especially mice, are essential for advancing hair loss research and treatment.
103 citations,
March 2015 in “Nature Communications” A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.
99 citations,
July 2017 in “Clinical Reviews in Allergy & Immunology” New treatments for Alopecia Areata show promise but need to be more effective and affordable.
70 citations,
January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.