Registrars’ Symposium: Summaries of Papers

June 2006 in “ British Journal of Dermatology ”

diffuse generalized hair loss postmenopausal women DHEAS adrenal androgens

TLDR Lower adrenal hormone levels may cause hair loss in postmenopausal women, certain patterns help diagnose nail cancer, and a gene variant linked to higher skin cancer risk in kidney transplant patients suggests monitoring folate levels.

The document summarizes three studies: the first study found that 14% of postmenopausal women experienced diffuse generalized hair loss, which was linked to lower levels of DHEAS but not to testosterone or SHBG, indicating a potential role for adrenal androgens in hair loss. The second study analyzed 20 cases of nail unit SCC over 8 years, identifying three characteristic patterns and underscoring the need for better recognition for timely diagnosis. The third study discovered a significant association between the MTHFR 677T allele and an increased risk of SCC in renal transplant patients, suggesting the importance of folate status monitoring in this population.

View this study on academic.oup.com →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 1 year ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community 7 months évolution of finasteride / zinc / vitamin D/ minoxidil / microneedling treatment

in Finasteride/Dutasteride 567 upvotes 2 years ago

User experienced hair loss improvement after 7 months using finasteride, zinc, vitamin D, minoxidil, and microneedling. Others praised the progress and discussed the importance of zinc and vitamin D in hair health.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 123 upvotes 11 months ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 489 upvotes 3 months ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Today I didn’t go to my cousin marriage because of my hair. I feel really depressed, I just want to disaper, i can’t take this anymore. I tried everything for the past 3 years, and I’m just 21 years. I’m isolating myself from othesrs.

in Finasteride/Dutasteride 284 upvotes 1 year ago

A 21 year-old feeling depressed about hair loss and how to cope with it, discussing various treatments such as finasteride, minoxidil, dutasteride, hair pieces, and scalp micropigmentation. There is also discussion of accepting oneself and redefining self-worth in order to not base one's entire identity on their hair.

Similar Research

5 / 1000+ results

research Female Pattern Alopecia: Current Perspectives

42 citations, August 2013 in “International Journal of Women's Health”

Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.

research Antiandrogen Therapy for Skin and Hair Disease

20 citations, April 2006 in “Dermatologic Clinics”

Antiandrogen therapies are beneficial for treating skin and hair conditions related to androgen levels.

research The Clinical Evaluation of Hirsutism

67 citations, September 2008 in “Dermatologic therapy”

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

research Hormonal Effects on Hair Follicles

102 citations, July 2020 in “International journal of molecular sciences”

Hormones like testosterone and estrogen significantly affect hair growth and structure.

research Endocrine Disorders and Infertility

1 citations, March 2011 in “Infertility”

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.