January 2024 in “Journal of Cutaneous and Aesthetic Surgery” This study describes a method to safely guard needles used in comedone extraction and scalp procedures during hair transplantation, aiming to prevent deep injuries and reduce patient fear.
This study found that proretinal nanoparticles, applied topically, are safe and effective for penetration into hair follicles, enhancing retinoid biological activity in the skin while reducing irritation compared to conventional retinal formulations.
October 2025 in “Transplantation” This study found that finasteride delivered through dissolving microneedles enhanced skin drug permeation compared to films, suggesting potential for improved androgenetic alopecia treatment with fewer side effects.
1 citations
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August 2024 in “European Journal of Medicinal Chemistry Reports” This systematic review examines the landscape of cosmetic microneedling using SWOT analysis, identifying strengths like precise delivery and self-administration, while noting challenges such as potential skin damage and regulatory issues, with opportunities in AI-enhanced targeted treatments noted by these researchers.
In this study, microneedling radiofrequency followed by topical exosome application was associated with significant increases in hair density and diameter, showing promising potential as a therapy for pattern hair loss.
Nanofat injection is safe and effective for improving skin texture and patient satisfaction.
January 2018 in “Journal of Visualized Experiments” This study found that injections of autologous platelet-rich plasma in patients with pattern hair loss were compared to placebo, but the abstract does not report specific clinical results.
39 citations
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June 2013 in “Journal of Cosmetic Dermatology” This study found that combining herbal extracts with PRP increased human dermal papilla cell proliferation via ERK and Akt protein regulation, suggesting its potential for developing hair growth therapies.
January 2023 in “Journal of Clinical and Diagnostic Research” This study compared the effectiveness and safety of microneedling with PRP versus minoxidil and finasteride topical therapy in adult males with androgenetic alopecia, finding similar hair density improvements in both groups, though microneedling with PRP had a quicker onset of action.
1 citations
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December 2016 in “Rossijskij žurnal kožnyh i veneričeskih boleznej” This study reported that 80% of patients with non-scarring alopecia showed a clinical cure after treatment with unactivated platelet leukocyte autoplasma.
5 citations
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December 2018 in “Journal of Cosmetic Dermatology” This study found that after treatment with platelet-rich plasma, male androgenetic alopecia patients showed significant improvements in hair count, hair diversity, and reduction in certain dermoscopic features.
1 citations
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January 2014 in “Aesthetic Plastic Surgery” Tattooing improves appearance of scalp alopecia and scars.
September 2024 in “Journal of Dental Specialities” This study found that platelet-rich plasma combined with micro-needling significantly increased hair density and thickness in patients with androgenetic alopecia, with mild side effects reported, though further high-quality trials are needed to validate these results and standardize treatments.
August 2025 in “Journal of the American Academy of Dermatology” The reported treatment depths were likely incorrect and could risk patient safety.
September 2024 in “Journal of Cosmetic Dermatology” Cold gel compresses are the best for pain relief during scalp microneedling.
September 2025 in “Frontiers in Pharmacology” This study found that the meropenem-loaded spanlastic formulation showed strong potential as an effective topical therapy for bacterial skin infections in non-diabetic mice, demonstrating superior therapeutic activity and wound healing compared to free meropenem.
28 citations
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February 2021 in “Dermatologic Surgery” This review found radiofrequency microneedling effective and safe for various dermatologic conditions, including skin rejuvenation and acne scars, especially in individuals with darker skin types, with progressive improvements for up to six months after treatment.
April 2025 in “Journal of Medical Residency Review” This review examined the use of platelet-rich plasma in aesthetic skin rejuvenation and found promising results when combined with other treatments, but limited efficacy when used alone.
April 2026 in “Journal of Cosmetic Dermatology” This review highlights the potential of combining microneedling with exosome therapy in treating various dermatological conditions, but emphasizes the need for more evidence regarding its safety and effectiveness.
4 citations
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June 2021 in “Wounds-a Compendium of Clinical Research and Practice” This study observed that erosive pustular dermatosis of the scalp in elderly patients was effectively treated with high-potency topical steroids, with plasma and lymphocyte dermal infiltrates helping to confirm diagnosis.
119 citations
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January 2014 in “Indian Journal of Dermatology, Venereology and Leprology” This review discusses the use of platelet-rich plasma in various dermatological applications and reports no new clinical results; the authors call for more rigorous trials to confirm its effectiveness.
November 2024 in “Siriraj Medical Journal/San Sirirat” In this study, a single platelet-rich plasma injection for facial rejuvenation improved patient satisfaction and skin elasticity, with the most notable effects occurring 1-2 weeks post-treatment.
March 2025 in “Stem Cell Research & Therapy” This study found that microneedles containing magnetic intracellular vesicles and tremella polysaccharide improved the hair microenvironment and accelerated hair regeneration in mice with androgenic alopecia.
June 2025 in “Aesthetic Cosmetology and Medicine” This article reviews the potential uses of PDRN in regenerative and aesthetic medicine, noting promising results in various treatments but highlighting the need for further long-term studies to confirm their safety and effectiveness.
1 citations
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January 2026 in “Science Advances” This study developed a 3D bioprinted skin model to mimic pemphigus vulgaris, providing a tool to study disease mechanisms and test targeted therapies by reproducing the architecture and pathogenic disruptions of native skin.
February 2006 in “Journal of The American Academy of Dermatology” This study found that Malassezia globosa, a scalp-associated fungus linked to dandruff, grows with saturated but not unsaturated fatty acids, potentially causing unsaturated fatty acid accumulation on the scalp and triggering dandruff-like flaking in susceptible individuals.
348 citations
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July 2017 in “Skin appendage disorders” This review discusses the use of platelet-rich plasma in dermatology for various applications such as tissue regeneration and wound healing, but it reports no new clinical results and calls for clearer guidance on suitable treatments.
September 2025 in “Universal library of medical and health sciences.” This study examined the use of medical dermapigmentation to restore lip appearance after traumatic injuries, finding that a staged approach effectively camouflages scar tissue, enhances symmetry, and improves psychological well-being, demonstrating benefits in a clinical case of a dog bite.
4 citations
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November 2020 in “Journal of Craniofacial Surgery” This study found that scalp micropigmentation minimized visible fading over time and led to high patient satisfaction in treating scalp pigmentation issues, with all participants willing to recommend the procedure.
December 2022 in “Small methods” This study developed dissolving microneedles incorporating a new AR degrader for treating androgenetic alopecia, showing that a single application leads to superior hair regeneration compared to daily minoxidil, without systemic toxicity or androgen-related issues.