Nanofat Injection for Facial Rejuvenation

January 2025

Nabil Fakih-Gomez, Roshini Manay, Dario Andres Bastidas

nanofat injection stromal vascular fraction adipose-derived stem cells ADSCs hair loss treatment

Studysummary Nanofat injection is safe and effective for improving skin texture and patient satisfaction. Our plain-language summary of this paper — not a Tressless recommendation.

Nanofat injection, a procedure that has evolved since 2013, utilizes filtered lipid containing tissue stromal vascular fraction and adipose-derived stem cells (ADSCs) for its regenerative properties. This technique is used for skin rejuvenation, texture improvement, scar treatment, dark circles, and hair loss treatment. The document presents three cases and details the procedure, post-operative care, and potential complications. The findings suggest that nanofat treatment is safe and effective, leading to improved skin texture and high patient satisfaction.

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Research cited in this study

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Concentrated Nanofat: A Modified Fat Extraction Promotes Hair Growth in Mice via Stem Cells and Extracellular Matrix Components Interaction

research Concentrated Nanofat: A Modified Fat Extraction Promotes Hair Growth in Mice via Stem Cells and Extracellular Matrix Components Interaction

4 citations , September 2020 in “Annals of Translational Medicine”

This study found that concentrated nanofat, used alone or with decellularized nanofat, may enhance hair growth in mice by activating dermal papilla cells and the anagen phase.

research Use of Condensed Nanofat Combined With Fat Grafts to Treat Atrophic Scars

62 citations , October 2017 in “JAMA facial plastic surgery”

This study reported that using condensed nanofat combined with fat grafts significantly improved the aesthetic and functional aspects of atrophic facial scars in 20 patients, as assessed by both patients and plastic surgeons using the Patient and Observer Scar Assessment Scale.