The Use of Microneedling With Exosomes in Dermatology: A Systematic Review

April 2026 in “ Journal of Cosmetic Dermatology ”

Navnit Kaur Dhaliwal, Thurkga Moothathamby, Balamrit Singh Sokhal, Maria Angeliki Gkini

microneedling exosome therapy androgenetic alopecia skin aging hyperpigmentation active scarring enlarged pores

Studysummary This review highlights the potential of combining microneedling with exosome therapy in treating various dermatological conditions, but emphasizes the need for more evidence regarding its safety and effectiveness.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

This systematic review evaluates the combined use of microneedling and exosome therapy in dermatology, focusing on conditions such as androgenetic alopecia, skin aging, hyperpigmentation, active scarring, and enlarged pores. Out of 256 references, 8 studies with sample sizes ranging from 3 to 60 participants were included. The review suggests that while microneedling and exosomes show promise, more research with larger sample sizes and longer follow-up is needed to fully understand their safety and efficacy.

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