Adipose Mesenchymal Stem Cell-Derived Exosomes Versus Platelet-Rich Plasma Treatment for Photoaged Facial Skin: An Investigator-Blinded, Split-Face, Non-Inferiority Trial

    May 2025 in “ Journal of Cosmetic Dermatology ”
    Blanca Estupiñan, Karen Ly, David J. Goldberg
    Studysummary This study reports that adipose mesenchymal stem cell-derived exosomes and platelet-rich plasma both improved the condition of photoaged facial skin, with no significant difference in effectiveness between the two treatments, potentially offering a quicker and less invasive option for patients.
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    Research cited in this study 6

    1. Autologous Platelet Concentrates in Aesthetic Medicine Periodontology 2000 · 2024
    2. The Therapeutic, Diagnostic, And Prognostic Values Of Extracellular Vesicles (Exosomes) In Dermatology: A Systematic Review JAAD reviews. · 2024
    3. Compare The Efficacy Of PRP Intervention Vs Exosomes For Hair Loss: A Case Series Study 2024
    4. Update on Exosomes in Aesthetics Dermatologic surgery · 2022
    5. Combined Effect of Microneedling and Platelet-Rich Plasma for the Treatment of Acne Scars: A Meta-Analysis Frontiers in Medicine · 2022
    6. A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification Skin appendage disorders · 2017

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