Anal Involvement in Pemphigus Vulgaris: Study on Recurrence and Treatment Outcomes

    March 2006 in “ Journal of The American Academy of Dermatology ”
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    TLDR Most patients with anal Pemphigus Vulgaris had repeated episodes but fully recovered with treatment, without long-term problems.
    The document summarizes a study on anal involvement in Pemphigus Vulgaris (PV), revealing that 56% of patients had recurrent anal PV with an average of 2.4 episodes. Despite the severity, all patients responded to systemic and local therapy, with no long-term sequelae or functional deficits observed over an average follow-up of 53 months. The study suggests that while anal PV is relatively rare and associated with severe PV, effective treatment can lead to full recovery without lasting effects. No conflicts of interest or commercial support were reported.
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