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    Glossary Cytokine

    protein signaling molecule crucial for immune response and inflammation

    A cytokine is a type of protein that acts as a signaling molecule in the body, helping cells communicate with each other, especially in immune responses. They play a crucial role in regulating inflammation, immune system activity, and cell growth, making them important in both health and disease contexts, such as infections, autoimmune disorders, and even hair loss conditions like alopecia.

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    1. Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing 2015 · 176 citations
    2. Evaluation of Not-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems International Journal of Molecular Sciences · 2017 · 136 citations
    3. Cutaneous reactions to recombinant cytokine therapy Journal of The American Academy of Dermatology · 1995 · 105 citations
    4. Growth factors and cytokines in hair follicle development and cycling: recent insights from animal models and the potentials for clinical therapy Molecular Medicine Today · 1996 · 100 citations
    5. Cytokines and growth factors influence hair growth in vitro. Possible implications for the pathogenesis and treatment of alopecia areata Archives of Dermatological Research · 1996 · 91 citations
    6. Recent Advances in the Controlled Release of Growth Factors and Cytokines for Improving Cutaneous Wound Healing Frontiers in Cell and Developmental Biology · 2020 · 88 citations
    7. Ovarian leukocyte distribution and cytokine/chemokine mRNA expression in follicular fluid cells in women with polycystic ovary syndrome Human Reproduction · 2006 · 69 citations
    8. Extensive alopecia areata is reversed by IL-12/IL-23p40 cytokine antagonism The Journal of Allergy and Clinical Immunology · 2015 · 68 citations
    9. Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis 2012 · 47 citations
    10. Platelet-Released Growth Factors Modulate the Secretion of Cytokines in Synoviocytes under Inflammatory Joint Disease Mediators of Inflammation · 2017 · 38 citations
    11. Protein Kinase C δ Overexpressing Transgenic Mice Are Resistant to Chemically but not to UV Radiation–Induced Development of Squamous Cell Carcinomas: A Possible Link to Specific Cytokines and Cyclooxygenase-2 Cancer Research · 2006 · 35 citations
    12. Protein Kinase C Epsilon Signals Ultraviolet Light-induced Cutaneous Damage and Development of Squamous Cell Carcinoma Possibly Through Induction of Specific Cytokines in a Paracrine Mechanism¶ Photochemistry and Photobiology · 2005 · 28 citations
    13. Analysis of hidradenitis suppurativa–linked mutations in four genes and the effects of PSEN1-P242LfsX11 on cytokine and chemokine expression in macrophages Human Molecular Genetics · 2018 · 25 citations
    14. Cytokine Targeted Therapeutics for Alopecia Areata: Lessons from Atopic Dermatitis and Other Inflammatory Skin Diseases 2017 · 25 citations
    15. The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier Frontiers in Immunology · 2021 · 23 citations
    16. GENETIC CONTROL OF CYTOKINES Dermatologic clinics · 1996 · 23 citations
    17. Tsukushi is involved in the wound healing by regulating the expression of cytokines and growth factors Journal of Cell Communication and Signaling · 2014 · 21 citations
    18. Cytokine loaded layer-by-layer ultrathin matrices to deliver single dermal papilla cells for spot-by-spot hair follicle regeneration Journal of Materials Chemistry B · 2015 · 19 citations
    19. Adverse cutaneous reactions to chemotherapeutic agents and cytokine therapy Seminars in Cutaneous Medicine and Surgery · 1996 · 18 citations
    20. PROTECTION AGAINST CYTOSINE ARABINOSIDE-INDUCED ALOPECIA BY MINOXIDIL IN A RAT ANIMAL MODEL International Journal of Dermatology · 1995 · 17 citations
    21. Influence of interleukin‐1α on androgen receptor expression and cytokine secretion by cultured human dermal papilla cells Experimental Dermatology · 2006 · 14 citations
    22. Assessment of Cytokine-Mediated Signaling Pathway Dysregulation in Arm Skin After CO2 Laser Therapy Journal of lasers in medical sciences · 2019 · 13 citations
    23. From Primary MSC Culture of Adipose Tissue to Immortalized Cell Line Producing Cytokines for Potential Use in Regenerative Medicine Therapy or Immunotherapy International Journal of Molecular Sciences · 2021 · 13 citations
    24. Genetically predicted levels of circulating cytokines and the risk of six immune skin diseases: a two-sample Mendelian randomization study Frontiers in Immunology · 2023 · 8 citations
    25. Dihydrotestosterone, and Not Testosterone, Enhances the LPS-Induced Inflammatory Cytokine Gene Expression in Human Adipocytes Biomedicines · 2023 · 7 citations
    26. Effects of cytokines, anti-cancer agents and cocarcinogen on DNA synthesis in hair bulb cells Journal of Dermatological Science · 1993 · 6 citations
    27. Cytokines and growth factors influence hair growth in vitro. Possible implications for the pathogenesis and treatment of alopecia areata Archives of Dermatological Research · 1996 · 5 citations
    28. Possible Immunomodulating Effect of Retinol on Cytokines Secretion in Patients with Recurrent Furunculosis Archivum Immunologiae et Therapiae Experimentalis · 2017 · 4 citations
    29. Cytokine Engineering Approaches for Regenerative Medicine Advanced Therapeutics · 2025 · 3 citations
    30. Protein Kinase C Epsilon Signals Ultraviolet Light‐induced Cutaneous Damage and Development of Squamous Cell Carcinoma Possibly Through Induction of Specific Cytokines in a Paracrine Mechanism<sup>¶</sup> Photochemistry and Photobiology · 2005 · 3 citations