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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Spironolactone successfully treated hair loss in a 9-year-old girl.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Treat hair loss with finasteride, minoxidil, or surgery; consider side effects and severity.

Treat hair loss with medicine, continue indefinitely.

Ketoconazole shampoo with finasteride improves hair density in men with hair loss.

Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.

Hirsutism is too much hair growth in women like the pattern in men, often caused by high male hormones, and can be treated with hormone control and hair removal methods.

The method accurately measures the amount of ketoconazole in anti-dandruff shampoo and cream, and can also be used to monitor the drug in human plasma.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

The study created a new method to test drugs that affect hormone processing in skin.

Finasteride metabolism varies by age, sex, and P450 inducers, with males processing it faster.

Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Some oral medications may help treat central serous chorioretinopathy, especially eplerenone, but more research is needed.