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DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Acyzol could help treat conditions caused by zinc deficiency.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Certain drugs that block specific enzymes can help treat prostate diseases.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

The traditional herbal formulas Yongdamsagan-Tang and Paljung-san, along with the drug finasteride, can reduce inflammation and may work together without affecting each other's effectiveness against benign prostatic hyperplasia.

Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Adding soybean oil to Nonomuraea dietziae increases production of a beneficial compound by improving metabolism and enzyme systems.

Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Gene mutations can cause problems in male genital development.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.