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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Potential new drugs for treating PCOS were identified.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Certain drugs change freshwater snail shells to a "banana" shape.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

A group has developed therapies that show promise for treating cancer and various other conditions.

A new method accurately measures nine specific hormones in human blood.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

Certain drugs that block specific enzymes can help treat prostate diseases.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Minoxidil may work for hair loss by reducing androgen sensitivity and altering hormone-related enzymes.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.