research Type-2 Immunity Associated With Type-1 Related Skin Inflammatory Diseases: Friend Or Foe?
Type-2 immunity may influence skin diseases and could be targeted for treatment.
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research Elevation of Circulating DNAs of Disease-Associated Cytokines in Serum Cell-Free DNA from Patients with Alopecia Areata
Higher levels of certain DNAs in blood may indicate hair follicle damage in alopecia areata patients.
research Generating Detailed Intercellular Communication Patterns in Psoriasis at the Single-Cell Level Using Social Networking, Pattern Recognition, and Manifold Learning Methods to Optimize Treatment Strategies
New insights into cell communication in psoriasis suggest innovative drug treatments.
research The Effect of Topical Gel Secretome Hypoxic Mesenchymal Stem Cells on IL-6 and TGF-β Gene Expression in Male Wistar Alopecia-Like Rat Models Induced by Fluconazole
SH-MSCs gel reduced IL-6 and increased TGF-β, suggesting it could treat alopecia.
research Application of Second Near Infrared Fluorescence Imaging to Trace CelTrac1000-Labeled Hair Follicle Epidermal Neural Crest Stem Cells in Repairing Rat Facial Nerve Defects
NIR-II imaging effectively tracked stem cells that helped repair facial nerve defects in rats.
research Scarring Hair Follicle Destruction Is Driven by the Collapse of EGFR-Protected JAK-STAT1-Sensitive Stem Cell Immune Privilege
A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.
research Identification of Distinct Immune Signatures and Chemokine Networks in Scalp Inflammatory Diseases
Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.
research IL-33 Contributes to the Pathological Changes of Hair Follicles in Psoriasis: A Potential Target for Psoriatic Alopecia
IL-33 is linked to hair follicle damage in psoriasis and could be a treatment target for hair loss in this condition.
research IL-17 Axis Is a Significant Driver of Skin Inflammation in CARD14 Mutant Pityriasis Rubra Pilaris Model Mice
Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.
research Increased Expression of TSPEAR in Colorectal Cancer Predicts Poor Prognosis
High TSPEAR levels in colorectal cancer predict worse outcomes.
research Host Genetic Susceptibility and Impacts of Dietary Factors on COVID-19
Certain genes and nutrients like vitamin D, zinc, and omega fatty acids affect COVID-19 severity and infection risk.
research Increased Expression of TSPEAR in Colorectal Cancer Predicts Poor Prognosis
High TSPEAR levels in colorectal cancer predict worse outcomes.
research Psoriatic Alopecia in a Patient With Crohn's Disease: An Uncommon Manifestation of Tumor Necrosis Factor Alpha Inhibitors
A girl with Crohn's disease developed hair loss due to her increased medication, a rare side effect seen in some children.
research Updates in the Pathogenesis of Alopecia Areata
Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.
research Risk of Autoimmune Diseases in Patients with RASopathies: Systematic Study of Humoral and Cellular Immunity
Patients with RASopathies have a higher risk of autoimmune disorders and should be routinely screened.
research Drug Armamentarium for Alopecia Areata
No cure exists for alopecia areata, and treatments are personalized.
research Epidermal Wnt/Beta-Catenin Signaling Promotes Dermal Adipocyte Differentiation During Hair Follicle Morphogenesis and Regeneration
Wnt/beta-catenin signaling in the skin helps fat cell development during hair growth and repair.
research Spironolactone for Treatment of Concomitant Female Pattern Hair Loss in Scarring Alopecia Patients
Spironolactone safely and effectively treats hair loss in female scarring alopecia patients.
research Alopecia Areata-Like Presentations With Mogamulizumab Therapy
Mogamulizumab, a skin cancer drug, may cause hair loss similar to alopecia areata.
research Controlled Delivery of T-box21 Small Interfering RNA Ameliorates Autoimmune Alopecia in a C3H/HeJ Mouse Model
Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.
research TNF Inhibitor Induced Alopecia: An Unusual Form of Psoriasiform Alopecia That Breaks the Renbök Mold
Some hair loss drugs can cause a unique type of hair loss that resembles both psoriasis and alopecia.
research Lichen Planopilaris Is Characterized By Immune Privilege Collapse Of The Hair Follicle's Epithelial Stem Cell Niche
Lichen planopilaris may be an autoimmune disease causing hair loss due to immune system issues in hair follicles.
research Laser Capture Microdissection Reveals Transcriptional Abnormalities In Alopecia Areata Before, During, And After Active Hair Loss
Alopecia areata involves persistent gene abnormalities and immune activity, even in regrown hair, suggesting a risk of relapse.
research Dietary Habits in Japanese Patients with Alopecia Areata
Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.
research Human T-Lymphotropic Virus 1 (HTLV-1)-Associated Lichenoid Dermatitis Induced by CD8+ T Cells in HTLV-1 Carrier, HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis and Adult T-Cell Leukemia/Lymphoma
HTLV-1-associated lichenoid dermatitis (HALD) is linked to an immune response against HTLV-1-infected cells.
research Time-Course RNA-Seq Analysis Reveals Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Hair Follicle Growth Cycle in Goats
Melatonin affects different genes and pathways important for goat hair growth.
research The Immunology of the Porcine Skin and Its Value as a Model for Human Skin
Porcine skin is very similar to human skin, making it a useful model for research.
research The Expanding Significance of Keratin Intermediate Filaments in Normal and Diseased Epithelia
Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
research Recent Advances in the Pathogenesis of Autoimmune Hair Loss Disease Alopecia Areata
Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.
research Natural Killer Cells in Atopic and Autoimmune Skin Diseases
NK cells play a role in skin diseases like eczema and psoriasis.